Stem Cells inUmbilical Cord

Suzanne Kadereit

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Stem Cells inUmbilical Cord

机译：脐带干细胞

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Over the last decades, umbilical cord blood (UCB) has emerged as a novel stem cell source. Already as early as 1974 researchers had shown that UCB contains functional hematopoietic progenitor cells, that multi-lineage colony-forming units were presentand that cryopreservation was possible. This set the stage for cord blood as a source for clinical applications in hematological diseases. In 1989, the successful engraftment of UCB in a young patient with Fanconi's Anemia demonstrated the feasibility of transplanting UCB instead of bone marrow.

机译：在过去的几十年中，脐带血（UCB）已经成为一种新型的干细胞来源。早在1974年，研究人员就已经表明UCB包含功能性造血祖细胞，存在多谱系集落形成单位，并且可以进行冷冻保存。这为脐带血作为血液学疾病临床应用的来源奠定了基础。 1989年，成功地将UCB植入一位患有Fanconi贫血的年轻患者，证明了移植UCB代替骨髓的可行性。

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《Asia-Pacific Biotech News》 |2012年第7期|共3页
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Suzanne Kadereit;
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中图分类分子生物学;
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1. Stem Cells inUmbilical Cord [J] . Suzanne Kadereit Asia-Pacific Biotech News . 2012,第7期

机译：脐带干细胞
2. Human Umbilical Cord Mesenchymal Stromal Cells Support Viability of Umbilical Cord Blood Hematopoietic Stem Cells but not the "Stemness" of Their Progeny in Co-Culture [J] . Romanov Yu. A., Volgina N. E., Balashova E. E., Bulletin of experimental biology and medicine . 2017,第4期

机译：人的脐带间充质细胞支持脐带血造血干细胞的活力，但不是它们在共同培养中的“茎干”
3. Prevention and treatment of cerebral palsy with cord blood stem cells and cord-derived mesenchymal stem cells [J] . Haruo Shintaku Neural regeneration research . 2021,第4期

机译：脐带血干细胞的预防和治疗脑瘫和帘线衍生间充质干细胞
4. Intraspinal administration of TiO2 nanowired cerebrolysin with mesenchymal stem cells has superior neuroprotective effects on cord pathology and functional outcome following a focal spinal cord trauma [C] . Lianyuan Feng, Aruna Sharma, Feng Niu, Annual techconnect world innovation conference expo;Defense techconnect DTS conference;Annual nanotech conference expo;SBIR/STTR innovation conference . 2018

机译：脊髓内施用TiO2纳米线脑溶素与间充质干细胞对局灶性脊髓损伤后的脊髓病理和功能结局具有优异的神经保护作用
5. Effect of Ephrin-B3 on the Survival of Adult Rat Spinal Cord Derived Neural Stem/Progenitor Cells In Vitro and After Transplantation into the Injured Rat Spinal Cord. [D] . Fan, Xin Yan Susan. 2012

机译：Ephrin-B3对成年大鼠脊髓源性神经干/祖细胞的体外存活以及移植到受损大鼠脊髓后的存活率的影响。
6. Frozen Cord Blood Hematopoietic Stem Cells Differentiate into Higher Numbers of Functional Natural Killer Cells In Vitro than Mobilized Hematopoietic Stem Cells or Freshly Isolated Cord Blood Hematopoietic Stem Cells [O] . Martha Luevano, Anna Domogala, Michael Blundell, -1

机译：与动员的造血干细胞或新鲜分离的脐带血造血干细胞相比冷冻的脐带血造血干细胞在体外分化为更多的功能性自然杀伤细胞
7. Frozen cord blood hematopoietic stem cells differentiate into higher numbers of functional natural killer cells in vitro than mobilized hematopoietic stem cells or freshly isolated cord blood hematopoietic stem cells. [O] . Martha Luevano, Anna Domogala, Michael Blundell, 2014

机译：冷冻脐带血造血干细胞在体外分化成更多数量的功能性自然杀伤细胞，而不是动员的造血干细胞或新鲜分离的脐带血造血干细胞。

Stem Cells inUmbilical Cord

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