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首页> 外文期刊>Atherosclerosis >A little+a little equals a lot-Does the combination of modest increases of liver inflammation and plasma cholesterol augment atherosclerosis?
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A little+a little equals a lot-Does the combination of modest increases of liver inflammation and plasma cholesterol augment atherosclerosis?

机译:一点+一点等于很多-肝脏炎症适度增加和血浆胆固醇的组合会增加动脉粥样硬化吗?

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摘要

The increased prevalence of obesity, type 2 diabetes, and the metabolic syndrome has led to a massive increase in the number of patients with non-alcoholic fatty liver disease (NAFLD) in developed countries [1,2]. Thus, 20-30% of all adults in the general population and 70-90% of obese or diabetic patients in western countries have NAFLD [1 ]. Since NAFLD increases the risk of cardiovascular death markedly [3-7], it is of great scientific and clinical importance to understand the mechanisms by which a disease in the liver can affect cardiovascular risk.
机译:肥胖,2型糖尿病和代谢综合征的患病率增加,导致发达国家非酒精性脂肪肝病(NAFLD)患者的数量大量增加[1,2]。因此,西方国家总人口中所有成年人的20-30%和肥胖或糖尿病患者的70-90%患有NAFLD [1]。由于NAFLD显着增加了心血管死亡的风险[3-7],因此了解肝脏疾病影响心血管风险的机制具有重大的科学和临床意义。

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