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首页> 外文期刊>Annales de biologie clinique >E hepatitis seroprevalence in a population of patients with transaminases increased at Le Mans' hospital (France)
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E hepatitis seroprevalence in a population of patients with transaminases increased at Le Mans' hospital (France)

机译:勒芒医院的转氨酶患者中的戊型肝炎血清阳性率升高(法国)

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摘要

In Europe, infection through the hepatitisEvirus presents itself under the form of autochthone, sporadic cases with zoonotic transmission. The diagnosis is more frequent in the case of male subjects above 50, with a generally severe clinical presentation. Moreover, a transition to chronicity is described in the case of immunocompromised patients. In France and in the world, seroprevalence has not clearly been established yet. In the hospital of Le Mans, Sarthe, France, the serologic status regarding the hepatitis E virus was established between October 1st 2012 and April 3rd 2015 on a population of 299 patients who presented hypertransaminasaemia and negative serology regarding hepatitis A, B and C viruses. According to the Wantai (R) Assays technique, seroprevalence for IgG among this cohort was 26.1%, while 3.7% of patients presented acute hepatitis E and a positive IgM serology. Hepatitis E screening tests are indispensable in the context of acute hepatitis no A, no B, no C.
机译:在欧洲,通过戊型肝炎病毒感染本身以散发人畜共患病的病例形式,即autochthone形式出现。在50岁以上的男性受试者中,诊断更为频繁,通常表现为严重的临床表现。此外,在免疫功能低下的患者中描述了向慢性的过渡。在法国乃至世界范围内,血清阳性率尚未明确建立。在法国萨特勒芒的医院,2012年10月1日至2015年4月3日之间建立了关于戊型肝炎病毒的血清学状况,该人群共有299名患者出现高转氨血症和有关甲型,乙型和丙型肝炎病毒的血清学阴性。根据Wantai(R)分析技术,该队列中IgG的血清阳性率为26.1%,而3.7%的患者表现为急性戊型肝炎和IgM血清学阳性。在没有甲,没有乙,没有丙的急性肝炎的情况下,戊型肝炎筛查测试是必不可少的。

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