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Antimicrobial activity of Actinomycetale isolated from the lagoon in Algeria

机译:从阿尔及利亚泻湖分离的放线菌的抗菌活性

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摘要

In the aim of the study of the taxonomy and the antimicrobial activity, a strain of actinomycete SM2/2GF which was isolated from sediment of Lthe lagoon El-Mellah which is situated in the city of El-Kala in the Northeast of Algeria, was tested against diverse pathogenic microorganisms and against a Gram-negative bacterium Pseudomonas alcaliphila which was isolated from water of the lagoon El-Mellah. The phenotypic and the molecular characteristics show that the isolate SM2/2GF belongs to the kind Streptomyces. This strain showed an antimicrobial activity against a Gram-negative bacterium Pseudomonas alcaliphila and the positive-Gram bacteria as Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Enterococcus faecalis, as well as the yeast Candida albicans. It has no activity against Pseudomonas aeruginosa. The interesting antimicrobial activity of the strain SM2/2GF against the pathogenic microorganisms could encourage further researches on one or several bioactive molecules which it secretes.
机译:为了研究分类学和抗菌活性,测试了从位于阿尔及利亚东北部El-Kala市的Lthe泻湖El-Mellah沉积物中分离的放线菌SM2 / 2GF菌株。分离自泻湖El-Mellah水中的革兰氏阴性假单胞菌(Pseudomonas alcaliphila)。表型和分子特征表明,分离株SM2 / 2GF属于链霉菌。该菌株对革兰氏阴性细菌嗜碱假单胞菌和阳性革兰氏细菌表现出抗微生物活性,如金黄色葡萄球菌,耐甲氧西林的金黄色葡萄球菌(MRSA),枯草芽孢杆菌,粪肠球菌以及白色念珠菌。它对铜绿假单胞菌没有活性。 SM2 / 2GF菌株对病原微生物的有趣的抗菌活性可以鼓励对其分泌的一种或几种生物活性分子的进一步研究。

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