首页> 外文期刊>Assiut Veterinary Medical Journal >PATHOLOGICAL AND BIOCHEMICAL CHANGES INDUCED BY AFLATOXIN IN CHICKENS AND A TRIAL FOR TREATMENT USING LACTOBACILLUS
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PATHOLOGICAL AND BIOCHEMICAL CHANGES INDUCED BY AFLATOXIN IN CHICKENS AND A TRIAL FOR TREATMENT USING LACTOBACILLUS

机译:黄曲霉毒素在雏鸡中引起的病理和生物化学变化以及使用乳酸杆菌治疗的试验

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摘要

This study was conducted to follow up broiler chickens during aflatoxicosis by feeding them with ration contaminated with Aflatoxin B1 (AFB 1) for a period of six weeks from 0 to 42 days; and to evaluate the effectiveness of Nutritox (a commercial biological antimycotoxin) in alleviating aflatoxicosis. One hundred broiler chicks of one day old were divided into four groups; each of twenty five chicks; the 1st group received a standard ration and kept as a control group, the 2nd group receiveda ration contaminated with 1 mg AFBl/kg ration, the 3rd group received ration contaminated withl mg AFBl/Kg ration plus Nutritox with a dose level 0.5gm/kg ration, the 4th group received a standard ration plus Nutritox with a dose level of 0.5 gm/kg ration. Chicks in all groups were weighed at the first and the end day of the experiment (42 days) and feed consumption for each group was calculated, blood and tissue samples were collected from each group at the end of the experiment. Results of the experiment revealed that AFB1 induced reduction in the body weight and feed consumption, while addition of Nutritox to the ration of chicks received AFB1 contaminated ration resulted in an improvement in the body weight and feed consumption compared with thatgroup received contaminated ration with AFB1 which elicited a significant increase in the activity of liver and kidney enzymes with decrease in calcium and inorganic phosphorus levels. Addition of Nutritox to contaminated ration induced a significant improvement in enzymes, calcium and phosphorus levels. Regarding the histopathological results, examination of the internal organs sections revealed typical lesions of Aflatoxicosis, but addition of Nutritox to AFB1 contaminated ration decreased the severity of the pathological lesions. The body weight of chicks of the control group, feed consumption and most of the studied biochemical parameters were improved, these findings suggest that the AFB 1, caused many alteration in the growth performance, and the biochemical parameters which are confirmed by many pathological changes in the internal oranges of the chicks. Addition of Nutritox to AFB1, contaminated ration was effective in alleviating the toxic effects associated with Aflatoxicosis.
机译:这项研究的目的是在肉毒中毒期间对肉鸡进行随访,方法是给它们饲喂被黄曲霉毒素B1(AFB 1)污染的食物,时间为0至42天,为期6周。并评估Nutritox(一种商业化的生物抗霉菌毒素)在减轻黄曲霉毒素中毒方面的有效性。将一百只一天大的雏鸡分成四组,每组四只。二十五只小鸡中的每只;第一组接受标准口粮并作为对照组,第二组接受被1 mg AFBl / kg口粮污染的口粮,第三组接受被1 mg AFBl / Kg口粮加上Nutritox污染的口粮,剂量水平为0.5gm / kg定量,第4组接受标准定量加Nutritox,剂量水平为0.5 gm / kg定量。在实验的第一天和结束时(42天)称重所有小鸡的体重,计算每组的饲料消耗量,在实验结束时从每组中收集血液和组织样本。实验结果表明,AFB1引起体重和饲料消耗的减少,而添加了Atrix的小鸡日粮中添加了Nutritox,与被AFB1污染的日粮相比,AFB1改善了体重和饲料消耗。引起肝脏和肾脏酶活性的显着增加,同时钙和无机磷水平降低。将Nutritox添加到受污染的日粮中可以显着改善酶,钙和磷的水平。关于组织病理学结果,对内脏切片的检查显示出典型的黄曲霉病病灶,但是向被AFB1污染的食物中添加Nutritox可以减轻病理病灶的严重程度。对照组雏鸡的体重,饲料消耗和大多数研究的生化参数均得到改善,这些发现表明AFB 1引起了许多生长性能的改变,而生化参数已被许多病理改变所证实。小鸡的内部橘子。在AFB1中添加受污染的Nutritox,可有效缓解与黄曲霉病相关的毒性作用。

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