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首页> 外文期刊>Biocontrol Science >Bulk and/or surface modification of medical polymers to attain antimicrobial activity and/or biocompatibility.
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Bulk and/or surface modification of medical polymers to attain antimicrobial activity and/or biocompatibility.

机译：医用聚合物的本体和/或表面改性以获得抗菌活性和/或生物相容性。

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摘要

In recent years, there has been a great demand for polymers designed with better functions that include blood and tissue compatibility (biocompatibility) and an antimicrobial activity. The surface modification of existing polymers is one of the most attractive ways to accomplish this. Treatment with plasma, gamma ray or electron beam leads to a sufficient level of activation of polymers so that specific monomers may be grafted. The extent of modification, i.e., the degree of grafting, may be easily controlled by the careful manipulation of the radiation exposure and reaction conditions. Graft modification may be carried out almost on all polymers with the creation of a desired functional chemistry both on the surface and in the bulk matrix. The grafting is applicable to almost all polymer-monomer combinations with enormous possibilities regarding physicochemical and biological characteristics to attain appropriate antimicrobial activity as well as suitable biocompatibility..
机译：近年来，人们对设计具有更好功能的聚合物的需求很大，这些功能包括血液和组织的相容性（生物相容性）以及抗菌活性。现有聚合物的表面改性是实现这一目标的最有吸引力的方法之一。用等离子体，伽马射线或电子束进行处理可以使聚合物充分活化，从而可以接枝特定的单体。修饰的程度，即接枝度，可以通过小心地控制辐射暴露和反应条件来容易地控制。几乎可以在所有聚合物上进行接枝改性，并在表面和本体基质中产生所需的功能化学。接枝适用于几乎所有的聚合物-单体组合，在理化和生物学特性方面具有巨大的可能性，以获得合适的抗菌活性和合适的生物相容性。

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