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首页> 外文期刊>Auris, nasus, larynx >Effect of edaravone on acute brainstem-cerebellar infarction with vertigo and sudden hearing loss
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Effect of edaravone on acute brainstem-cerebellar infarction with vertigo and sudden hearing loss

机译：依达拉奉对急性脑干-小脑梗死伴眩晕和突然听力下降的影响

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摘要

We report 2 cases with acute brainstem and brainstem-cerebellar infarction showed improvement of their signs and symptoms after administration of edaravone. Case 1, a 74-year-old woman who experienced sudden vertigo, also had dysarthria and left hemiplegia. Magnetic resonance imaging (MRI) showed an abnormal region in the right ventrolateral medulla oblongata. The patient's vertigo and hemiplegia improved completely after treatment. Case 2, a 50-year-old man who experienced sudden vertigo and sensorineural hearing loss (SNHL), developed dysarthria after admission. MRI revealed acute infarction in the right cerebellar hemisphere. Magnetic resonance angiography revealed dissection of the basilar artery and occlusion of the right anterior inferior cerebellar artery. The patient's vertigo and hearing remarkably improved. We have described 2 patients whose early symptoms were vertigo and sudden SNHL, but who were later shown to have ischemic lesions of the central nervous system. Edaravone is neuroprotective drug with free radical-scavenging actions. Free radicals in the ear are responsible for ischemic damage. Edaravone, a free radical scavenger, may be useful in the treatment of vertigo and SNHL.
机译：我们报告2例急性脑干和脑干-小脑梗死患者在服用依达拉奉后表现出体征和症状改善。病例1，是一位74岁的女性，她经历了突然的眩晕，也有构音障碍和左偏瘫。磁共振成像（MRI）显示右腹外侧延髓中有异常区域。治疗后患者的眩晕和偏瘫完全改善。病例2，一个50岁的男子，他突然出现眩晕和感觉神经性听力损失（SNHL），入院后出现了构音障碍。 MRI显示右小脑半球急性梗死。磁共振血管造影显示了基底动脉的解剖和右前小脑下动脉的闭塞。病人的眩晕和听力明显改善。我们描述了2例早期症状为眩晕和突然SNHL的患者，但后来被证实患有中枢神经系统缺血性病变。依达拉奉是具有自由基清除作用的神经保护药物。耳朵中的自由基是缺血性损伤的原因。依达拉奉是一种自由基清除剂，可用于治疗眩晕和SNHL。

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