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Anti pseudorabies virus activity of kumazasa extract.

机译:kumazasa提取物的抗伪狂犬病病毒活性。

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Sasa veitchii or "kumazasa" has been used for the preservation of food, or preventing bacterial activity. However, the antiviral activity of kumazasa is poorly understood. In the present study, the antiviral activity of kumazasa extract (KE) was assessed by the plaque reduction assay for the pseudorabies virus (PRV). KE reduced 99% of the plaque formation of PRV at concentrations of 1.2%, showing that KE inhibited PRV adsorption to cells and IE180 expression. The polysaccharide fraction of KE showed a concentration dependent inhibition of PRV plaque formation. We conclude that KE possesses potent anti PRV activity, and the candidate responsible for the antiviral property was the polysaccharide fraction.
机译:Sasa veitchii或“ kumazasa”已用于保存食物或防止细菌活动。然而,人们对库马佐的抗病毒活性了解甚少。在本研究中,通过伪狂犬病病毒(PRV)的噬斑减少测定法评估了苦味提取物(KE)的抗病毒活性。 KE在1.2%的浓度下可减少99%的PRV斑块形成,表明KE抑制了PRV对细胞的吸附和IE180表达。 KE的多糖部分显示PRV斑块形成的浓度依赖性抑制。我们得出的结论是,KE具有强大的抗PRV活性,而负责抗病毒特性的候选对象是多糖部分。

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