...
首页> 外文期刊>Aviation, space, and environmental medicine. >Leptin and ghrelin levels in humans during physical inactivity induced by head-down bed rest.
【24h】

Leptin and ghrelin levels in humans during physical inactivity induced by head-down bed rest.

机译:头朝下卧床休息引起的身体不活动时人体中的瘦素和生长素释放肽水平。

获取原文
获取原文并翻译 | 示例
           

摘要

INTRODUCTION: The aim of this study was to investigate the consequences of 20 d of physical inactivity using head-down bed rest (HDBR) at -6 degrees on leptin, ghrelin, and counter-regulatory hormone responses. METHODS: Eight male volunteers were subjected to HDBR for 20 d. Variables measured before, during, and after HDBR included plasma cortisol, insulin, glucose, leptin, ghrelin, thyroid stimulating hormone (TSH), free thyroxine (fT4), and free triiodothyronine (fT3). RESULTS: No changes in ghrelin and leptin concentrations were observed during HDBR. Glucose concentration decreased significantly on the 20th day of HDBR compared to the pre-value (day 0) of HDBR (87.6 +/- 2.0 vs. 93 +/- 1.6 mg x dl(-1)). Significant correlation was observed between glucose and leptin concentrations. DISCUSSION: The results provide the first evidence that 20 d of HDBR is not associated with an alteration in ghrelin concentration. Leptin, insulin, and cortisol concentrations did not differ during 20 d of HDBR.
机译:引言:本研究的目的是调查在-6度下使用头朝下卧床休息(HDBR)进行20 d的体育锻炼对瘦素,生长激素释放肽和逆调节激素反应的影响。方法:8名男性志愿者接受HDBR治疗20 d。在HDBR之前,之中和之后测量的变量包括血浆皮质醇,胰岛素,葡萄糖,瘦素,生长素释放肽,甲状腺刺激激素(TSH),游离甲状腺素(fT4)和游离三碘甲状腺素(fT3)。结果:HDBR期间未观察到生长素释放肽和瘦素浓度的变化。与HDBR的前值(第0天)相比,HDBR在第20天的葡萄糖浓度显着降低(87.6 +/- 2.0与93 +/- 1.6 mg x dl(-1))。在葡萄糖和瘦素浓度之间观察到显着相关性。讨论:该结果提供了第一个证据,即20 d的HDBR与生长素释放肽浓度的变化无关。 HDBR 20 d期间,瘦素,胰岛素和皮质醇浓度无差异。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号