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首页> 外文期刊>Biocontrol Science >Antibacterial Activity and Characteristics of Modified Ferrite Powder Coated with a Gemini Pyridinium Salt Molecule
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Antibacterial Activity and Characteristics of Modified Ferrite Powder Coated with a Gemini Pyridinium Salt Molecule

机译：双子座吡啶盐分子包覆的改性铁氧体粉末的抗菌活性和特性

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摘要

This report describes the synthesis of an antibacterial material consisting of a gemini quaternary ammonium salt (gemini-QUAT) Immobilized on ferrite powder, and its antibacterial activity. A gemini-QUAT containing two pyridinium residues per molecule, 4,4'-[1,3-(2,2-dlhydroxylmethyl-1,3-dithiapropane)]bis (1-octylpyridinium bromide), was immobilized on ferrite powder by a reaction between the hydroxyl group of the QUAT and trimethoxysilane. Immobilization of the gemini-QUAT on ferrite (F-gemini-QUAT) was confirmed when the dye, bromophenol blue, was released from F-gemini-QUAT-dye after contact between ferrite and the dye. Elemental analysis of the QUAT-ferrite determined the molar amount of QUAT on the ferrite. The antibacterial effect of the ferrite was investigated using a batch treatment system, and this effect was compared with that of another QUAT-ferrite (F-mono-QUAT) binding a mono-QUAT, which possesses one pyridinium residue, prepared by the same immobilization method as F-gemini-QUAT. Results indicated the F-gemini QUAT possessed a higher bactericidal potency and broader antibacterial spectrum compared to F-mono-QUAT. In addition, this study suggested that gemini-QUATs possessed high bactericidal potency without being influenced by immobilization to materials, and the antibacterial activity and characteristics of F-gemini-QUAT could be attributed to the unique structure of the immobilized gemini-QUAT.
机译：该报告描述了固定在铁氧体粉末上的由双子座季铵盐（gemini-QUAT）组成的抗菌材料的合成及其抗菌活性。每个分子含有两个吡啶鎓残基的双子座-QUAT，将4,4'-[1,3-（2,2-二羟甲基-1,3-二硫丙烷）]双（1-辛基溴化吡啶鎓）通过铁固定在铁氧体粉末上。 QUAT的羟基与三甲氧基硅烷之间的反应。当铁氧体与染料接触后，从F-gemini-QUAT染料中释放出溴酚蓝染料时，证实了双子座-QUAT固定在铁氧体上（F-gemini-QUAT）。 QUAT铁氧体的元素分析确定了QUAT在铁氧体上的摩尔量。使用分批处理系统研究了铁氧体的抗菌作用，并将该作用与通过相同固定化方法制备的另一种结合具有一个吡啶鎓残基的mono-QUAT的QUAT铁氧体（F-mono-QUAT）的抗菌作用进行了比较。方法为F-gemini-QUAT。结果表明，与F-mono-QUAT相比，F-gemini QUAT具有更高的杀菌力和更广的抗菌谱。此外，这项研究表明，双子蛋白-QUAT具有高杀菌力，而不受固定化材料的影响，而F-双子蛋白-QUAT的抗菌活性和特性可归因于固定化的双子蛋白-QUAT的独特结构。

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