Using atlas of heart shapes for simulation of blood flow in left ventricle

Moosavi M.-H.; Fatouraee N.; Katoozian H.; Pashaei A.; Frangi A.F.

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Using atlas of heart shapes for simulation of blood flow in left ventricle

机译：使用心脏形状图谱模拟左心室的血流

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Integrative modeling of cardiac system is important for understanding the complex biophysical function of the heart]. To this end, multimodal cardiovascular imaging plays an important role in providing the computational domain, the boundary/initial conditions, and tissue function and properties. In particular, the incorporation of blood flow in the physiological models can help to simulate the hemodynamic properties and their effects on cardiac function. In this paper, we present a multimodal framework for quantitative and subject-specific analysis of blood flow in the cardiac chambers, including the left ventricle (LV). The 3D geometries of the LV at different time steps are extracted from medical images using an atlas of LV shape. The motion of the myocardium wall is used to extract the moving boundary data of the computational geometry. The data is used as a constraint for the computational fluid dynamics (CFD). An arbitrary Lagrangian-Eulerian (ALE) finite element method (FEM) formulation is used to derive a numerical solution of the transient dynamic equation of the fluid domain. With this method, simulation results describe detailed flow characteristics (such as velocity, pressure and wall shear stress) in the computational domain. The personalized hemodynamic characteristics obtained with the proposed approach can provide clinical value for diagnosis and treatment of abnormalities related to disturbed blood flow such as in myocardial remodeling and aortic sinus lesion formation.

机译：心脏系统的综合建模对于理解心脏的复杂生物物理功能很重要。为此，多峰心血管成像在提供计算范围，边界/初始条件以及组织功能和特性方面起着重要作用。特别地，将血流纳入生理模型可以帮助模拟血液动力学特性及其对心脏功能的影响。在本文中，我们提出了一种多模式框架，用于定量和特定于对象的心脏腔（包括左心室（LV））中的血流分析。使用LV形状图集从医学图像中提取不同时间步长的LV 3D几何形状。心肌壁的运动用于提取计算几何形状的运动边界数据。该数据用作计算流体动力学（CFD）的约束。使用任意拉格朗日-欧拉（ALE）有限元方法（FEM）公式来导出流域瞬态动力学方程的数值解。使用这种方法，模拟结果在计算域中描述了详细的流动特性（例如速度，压力和壁切应力）。通过所提出的方法获得的个性化血液动力学特征可以为诊断和治疗与血流紊乱有关的异常提供临床价值，例如在心肌重塑和主动脉窦病变的形成中。

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《Biomedical Engineering: Applications, Basis and Communications》 |2013年第6期|共8页
作者
Moosavi M.-H.; Fatouraee N.; Katoozian H.; Pashaei A.; Frangi A.F.;
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正文语种 eng
中图分类医用一般科学;
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Blood flow simulation; Computational fluid dynamics; Medical imaging;

机译：血流模拟;计算流体力学;医学成像;

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专利

1. Using atlas of heart shapes for simulation of blood flow in left ventricle [J] . Moosavi M.-H., Fatouraee N., Katoozian H., Biomedical Engineering: Applications, Basis and Communications . 2013,第6期

机译：使用心脏形状图谱模拟左心室的血流
2. Numerical simulation of blood flow in the left ventricle and aortic sinus using magnetic resonance imaging and computational fluid dynamics [J] . Mir-Hossein Moosavi, Nasser Fatouraee, Hamid Katoozian, Computer methods in biomechanics and biomedical engineering . 2014,第5a8期

机译：磁共振成像和流体力学计算对左心室和主动脉窦血流的数值模拟
3. A new uniform parameterization and invariant 3D spherical harmonic shape descriptors for shape analysis of the heart's left ventricle - A pilot study [J] . A. Ben Abdallah, rnF. Ghorbel, rnK. Chatti, Pattern recognition letters . 2010,第13期

机译：用于心脏左心室形状分析的新的均匀参数化和不变的3D球面谐波形状描述符-初步研究
4. A High Performance Computing Framework for Finite Element Simulation of Blood Flow in the Left Ventricle of the Human Heart [C] . Jeannette Hiromi Spuehler, Johan Jansson, Niclas Jansson, Conference on finite elements in flow . 2017

机译：一种用于人心脏左心室血流有限元模拟的高性能计算框架
5. Image-Based CFD Simulation of Blood Flow in the Left Ventricle via Echocardiography Data in a Fluid-Structure Interaction (FSI) Framework [D] . Mehri, Mohammad. 2021

机译：在流体 - 结构相互作用（FSI）框架中，通过超声心动图数据（FSI）框架中的基于图像的血流血流血流模拟
6. Application of Atlas-based global shape and local contraction analysis to single-ventricle congenital heart disease [O] . Avan Suinesiaputra, Genevieve E Farrar, Kathleen Gilbert, 2016

机译：基于Atlas的整体形状和局部收缩分析在单室先天性心脏病中的应用
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Using atlas of heart shapes for simulation of blood flow in left ventricle

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