• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biomedical Engineering: Applications, Basis and Communications >Simulation of pulsatile blood flow through stenotic artery considering different blood rheologies: Comparison of 3D and 2D-axisymmetric models
【24h】

Simulation of pulsatile blood flow through stenotic artery considering different blood rheologies: Comparison of 3D and 2D-axisymmetric models

机译：考虑不同血液流变性的通过狭窄动脉的搏动血流模拟：3D和2D轴对称模型的比较

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Hemodynamic factors such as velocity distribution, pressure gradient and wall shear stress are thought to play an important role in the prognosis of symptomatic carotid occlusion. Although there are many studies about modeling the blood flow behavior in carotid, hemodynamic characteristics of blood flow in a stenosed carotid artery is still debatable. In this study a three-dimensional (3D) model of a symmetric stenosed common carotid artery (CCA) is developed and the simulation results of it are compared to the experimental data where subsequent agreement is confirmed. To study the accuracy of two-dimensional (2D) axisymmetric model, the result of it is compared to the result of the 3D model. Two non-Newtonian rheological models, namely Carreau and modified Power-law, as well as Newtonian model are used to realize the hemodynamical differences of 2D-axisymmetric and 3D models in pulsatile blood flow. Comparing the 3D simulated results with 2D-axisymmetric modeling results that were published in recent years indicates that the assumption of 2D-axisymmetric model cannot adequately predict the velocity profiles even for a symmetric stenotic artery. Although a symmetric stenotic artery is considered, the results indicate a nonsymmetric flow in poststenosis region that is detected by the presence of extensive secondary flows particularly at diastole. The existence of secondary flows that can only be detected in 3D modeling is the main reason for the differences in hemodynamic factors in 3D and 2D results.
机译：血液动力学因素如速度分布，压力梯度和壁切应力被认为在有症状的颈动脉闭塞的预后中起重要作用。尽管有许多关于模拟颈动脉血流行为的研究，但狭窄的颈动脉血流的血流动力学特征仍然值得商bat。在这项研究中，建立了对称的狭窄颈总动脉（CCA）的三维（3D）模型，并将其模拟结果与实验数据进行了比较，从而确定了后续协议。为了研究二维（2D）轴对称模型的准确性，将其结果与3D模型的结果进行比较。使用两个非牛顿流变模型，即Carreau模型和修正的幂律模型，以及牛顿模型，来实现2D轴对称和3D模型在脉动血流中的血液动力学差异。将3D模拟结果与近年来发布的2D轴对称模型结果进行比较表明，即使对于对称的狭窄动脉，2D轴对称模型的假设也无法充分预测速度分布。尽管考虑了对称的狭窄动脉，但结果表明狭窄后区域中存在不对称血流，这可通过存在大量次生血流（尤其是在舒张期）来检测。只能在3D建模中检测到的辅助流的存在是3D和2D结果中血液动力学因素差异的主要原因。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号