• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Nutritional Science and Vitaminology >Effect of Momordica charantia on Insulin Immune-Reactive Pancreatic Beta Cells and Blood Glucose Levels in
【24h】

Effect of Momordica charantia on Insulin Immune-Reactive Pancreatic Beta Cells and Blood Glucose Levels in

机译：Effect of Momordica charantia on Insulin Immune-Reactive Pancreatic Beta Cells and Blood Glucose Levels in

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

The present study was conducted to determine the antidiabetic effect of Momordica charantia (MC) on pancreatic islets of Langerhans in streptozotocin (STZ)-induced diabetic male Wistar rats in relation to the distribution of insulin immuno-positive beta cells. MC was fed to rats at 2, 5, and 10 of the standard diet for 12 wk. After sacrification, the pancreatic tissues were obtained for histopathological and immunohistochemical observations. In addition, monitoring of fasting blood glucose was applied each month during experimental period. The results revealed that the oral doses of MC at 5 and 10 of the daily diet increased the percentage of insulin-positive pancreatic beta cells as well as the size and number of pancreatic islets. Moreover, significant (p LE;0.0001) dose and time-depended reduction in fasting blood glucose levels were observed. In conclusion, these results suggest that MC induces antidiabetic effects via regeneration of insulin-positive pancreatic beta cells and increase the number of insulin secretory granules hence, blood glucose reduction.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号