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首页> 外文期刊>Biomedical Engineering: Applications, Basis and Communications >Lower limb joint position sense in patients with type II diabetes mellitus
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Lower limb joint position sense in patients with type II diabetes mellitus

机译：II型糖尿病患者的下肢关节位置感

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Diabetes mellitus (DM), of which type II has been described as an international epidemic, is a major cause of death. Diabetic peripheral neuropathy (PN) is a condition secondary to hyperglycemia, where progressive loss of peripheral nerve function, including sensory and motor functions, occurs over time. Early detection of PN-related impairments may be helpful for the management of patients with DM. Among the methods for the evaluation of these impairments, only that for joint position sense (JPS) requires both motor and sensory involvement. The purpose of the current study was to compare the JPS of the lower limb joints in patients with no or mild diabetic PN to those of normal controls both during weight-bearing (WB) and non-weight-bearing (NWB) conditions using 3D motion analysis methods. The results supported the hypothesis that in well controlled diabetic patients with no or mild PN, JPS deficits can be found only at the ankle joint during WB conditions, resulting in overestimation of dorsiflexion angles. This suggests that at the very early stage of development of diabetic PN, distal joint involvement precedes that of proximal joints. Early detection of these changes, through the assessment of the JPS for all the lower limb joints under both NWB and WB conditions, will be helpful for the development of clinical preventive and treatment programs for patients with DM, even if their glucose level are well controlled. Gait and balance training in these patients should emphasize proprioception training exercises during WB conditions.
机译：II型糖尿病已被描述为国际流行病，是造成死亡的主要原因。糖尿病性周围神经病（PN）是高血糖继发的疾病，随着时间的流逝，周围神经功能（包括感觉和运动功能）逐渐丧失。早期发现与PN相关的损伤可能有助于DM患者的管理。在评估这些损伤的方法中，只有关节位置感知（JPS）的方法需要运动和感觉的参与。本研究的目的是使用3D动作比较在无负重（Nb）和负重（NWB）情况下无或轻度糖尿病PN的患者下肢关节的JPS与正常对照的患者分析方法。该结果支持以下假设：在无PN或轻度PN且控制良好的糖尿病患者中，仅在WB情况下仅在踝关节处发现JPS缺陷，从而导致背屈角的过高估计。这表明在糖尿病性PN发展的非常早期，远端关节受累先于近端关节。通过评估NWB和WB条件下所有下肢关节的JPS来及早发现这些变化，即使其血糖水平得到良好控制，也将有助于制定DM患者的临床预防和治疗计划。这些患者的步态和平衡训练应强调在WB条件下的本体感受训练练习。

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