Development of human lymphoid cells.

Blom B; Spits H

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Development of human lymphoid cells.

机译：人类淋巴样细胞的发育。

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The lymphocytes, T, B, and NK cells, and a proportion of dendritic cells (DCs) have a common developmental origin. Lymphocytes develop from hematopoietic stem cells via common lymphocyte and various lineage-restricted precursors. This review discusses the current knowledge of human lymphocyte development and the phenotypes and functions of the rare intermediate populations that together form the pathways of development into T, B, and NK cells and DCs. Clearly, development of hematopoietic cells is supported by cytokines. The studies of patients with genetic deficiencies in cytokine receptors that are discussed here have illuminated the importance of cytokines in lymphoid development. Lineage decisions are under control of transcription factors, and studies performed in the past decade have provided insight into transcriptional control of human lymphoid development, the results of which are summarized and discussed in this review.

机译：淋巴细胞，T，B和NK细胞以及一定比例的树突状细胞（DC）具有共同的发育起源。淋巴细胞从造血干细胞通过普通淋巴细胞和各种谱系限制的前体发育而来。这篇综述讨论了人类淋巴细胞发育的当前知识以及罕见的中间种群的表型和功能，这些共同构成了向T，B和NK细胞和DC发育的途径。显然，造血细胞的发育受到细胞因子的支持。本文讨论的对细胞因子受体遗传缺陷患者的研究揭示了细胞因子在淋巴发育中的重要性。世系的决定受转录因子的控制，过去十年来进行的研究提供了对人类淋巴发育的转录控制的见识，其结果在本综述中进行了总结和讨论。

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《Annual Review of Immunology》 |2006年第0期|共34页
作者
Blom B; Spits H;
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正文语种 eng
中图分类基础医学;
关键词
development aspects; Lymphocytes; Human; 淋巴细胞;

机译：development aspects;Lymphocytes;Human;淋巴细胞;

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专利

1. Development of human lymphoid cells. [J] . Blom B, Spits H Annual Review of Immunology . 2006,第0期

机译：人类淋巴样细胞的发育。
2. An antigen shared by a human T cell subset and B cell chronic lymphocytic leukemic cells. Distribution on normal and malignant lymphoid cells. [J] . L Boumsell, H Coppin, D Pham, The Journal of Experomental Medicine . 1980,第1期

机译：人类T细胞亚群和B细胞慢性淋巴细胞性白血病细胞共享的抗原。分布于正常和恶性淋巴样细胞。
3. Natural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells. [J] . Kaveri SV International immunology. . 2004,第3期

机译：天然人多反应性IgM诱导淋巴样细胞系和人外周血单核细胞凋亡。
4. A System for Accurate and Sensitive Measurements of Non-Human Glycoprotein Modifications on Human Embryonic Stem Cells. [C] . W. Travis Berggren, Kevin R. Conard, Tenneille E. Ludwig, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：一种用于对人胚胎干细胞的非人糖蛋白修饰的准确和敏感测量的系统。
5. Human Innate Lymphoid Cell Biology and Development [D] . Chen, Luxi. 2019

机译：人体先天淋巴细胞生物学和发展
6. Expression of 20 alpha-hydroxysteroid dehydrogenase activity in human lymphoid and non lymphoid cells. [O] . A Carbone, M Piantelli, P Musiani, 1986

机译：人淋巴和非淋巴细胞中20α-羟类固醇脱氢酶活性的表达。
7. Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. [O] . Meier, Dominik, Bornmann, Caroline, Chappaz, Stephane, 2007

机译：异位淋巴器官的发育是通过白介素7介导的淋巴组织诱导细胞的存活增强而发生的。
8. Viral Protein R of Human Immunodeficiency Virus Types 1 and 2 Is Dispensable for Replication and Cytopathogenicity in Lymphoid Cells. (Reannouncement with New Availability Information). [R] . Dedera, D., Hu, W., Vander Heyden, N., 1989

机译：人类免疫缺陷病毒1型和2型的病毒蛋白R对于淋巴细胞中的复制和致细胞病变是必不可少的。（重新公布新的可用性信息）。

Development of human lymphoid cells.

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