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首页> 外文期刊>American Journal of Hypertension >Correlation between peripheral blood pressure and pulse-wave velocity values in the institutionalized elderly persons 80 years of age and older: The PARTAGE study
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Correlation between peripheral blood pressure and pulse-wave velocity values in the institutionalized elderly persons 80 years of age and older: The PARTAGE study

机译:80岁及以上老年人的外周血压与脉搏波速度值之间的相关性:PARTAGE研究

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Background Carotid-femoral pulse-wave velocity (PWV) provides a comprehensive noninvasive indication of arterial stiffness, and is now established as a strong marker of cardiovascular disease (CVD). The correlation between peripheral blood pressure (BP) and PWV and their respective influences on mortality have been poorly studied in the elderly. Our objective was to analyze this correlation in nursing-home residents over 80 years of age, with the view that the Results of this could ultimately be helpful in implementing strategies for the diagnosis and long-term follow-up of CVD and mortality in the very elderly population. Methods The Predictive Value of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population (PARTAGE) study is a 2-year cohort study of 1,130 subjects living in 72 nursing homes in France and Italy. The correlation between baseline systolic and diastolic blood pressure (SBP and DBP, respectively) and baseline PWV (measured with a PulsePen? tonometer) was studied in 1,071 subjects for whom PWV measurements were available. Results Correlations between peripheral BP and PWV were significant but weak, with r = 0.24 for self-measured SBP, r = 0.30 for casual SBP, r = 0.11 for self-measured DBP, r = 0.14 for casual DBP, and r = 0.26 for casual pulse pressure (PP). A trend toward a weaker correlation was observed in the older age group for self-measured SBP and in the group with a lower level of activities of daily living (ADL) for self-measured SBP and DBP. Conclusions These findings suggest that SBP, DBP, and PWV provide different information in the very elderly. The Results of the prospective, longitudinal, long-term PARTAGE study will allow further insight into this and provide additional in-depth information about the respective prognostic value of the measurement of peripheral BP and PWV.
机译:背景颈股脉搏波速度(PWV)提供了动脉僵硬度的全面无创指征,现已被确立为心血管疾病(CVD)的有力标志。在老年人中,对外周血压(BP)和PWV及其对死亡率的影响的相关研究很少。我们的目的是分析80岁以上养老院居民中的这种相关性,认为其结果最终将有助于实施诊断和长期随访CVD和死亡率的策略。老年人口。方法高血压和动脉僵硬度在机构化高龄人口研究中的预测价值(PARTAGE)是一项为期2年的队列研究,研究对象是法国和意大利72个疗养院中的1,130名受试者。基线收缩压和舒张压(分别为SBP和DBP)与基线PWV(用PulsePenton眼压计测量)之间的相关性在1,071名可进行PWV测量的受试者中进行了研究。结果外周血压与PWV之间的相关性显着但微弱,自测SBP的r = 0.24,散装SBP的r = 0.30,自测DBP的r = 0.11,散装DBP的r = 0.14和散布的P = 0.26偶然脉压(PP)。在年龄较大的人群中,自我测量的SBP的趋势趋于弱,而在自我测量的SBP和DBP的日常生活活动水平较低的人群中,则呈下降趋势。结论这些发现表明SBP,DBP和PWV在老年人中提供了不同的信息。前瞻性,长期,长期PARTAGE研究的结果将使您对此有进一步的了解,并提供有关测量外周血压和PWV的各自预后价值的其他深入信息。

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