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首页> 外文期刊>Indian Journal of Scientific Research >INTRAVENOUS CONSCIOUS SEDATION IN UNCOOPERATIVE CHILDRENUNDERGOING DENTAL PROCEDURES: A COMPARATIVE EVALUATION OF MIDAZOLAM/ PROPOFOL AND KETAMINE/ PROPOFOL
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INTRAVENOUS CONSCIOUS SEDATION IN UNCOOPERATIVE CHILDRENUNDERGOING DENTAL PROCEDURES: A COMPARATIVE EVALUATION OF MIDAZOLAM/ PROPOFOL AND KETAMINE/ PROPOFOL

机译：儿童不宜进行牙科手术过程中的静脉自觉镇静作用：咪达唑仑/丙泊酚和氯胺酮/丙泊酚的比较评价

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摘要

There is a lack of clinical trials on pediatric dental sedation.We investigated efficacy of intravenous conscious sedation during dental treatment with Midazolam/ Propofol compared to Ketamine / Propofol in 4-6 years old children.In this prospective clinical trial study 38 healthy non-cooperative children candidate dental treatment under Intravenous conscious sedation randomly were divided into two groups. Intravenous conscious sedation in one group was performed by midazolam/ Propofol and in the other group carried out by Ketamine /propofol. The bispectral index and sedation score from Dental Sedation Teachers Group (DSTG) was employed for evaluating the sedation effect of each regimen by a one trained, blinded observer.The working conditions for each patient were assessed at the end of the treatment, using the rating scale by DSTG and the time taken to achieve discharge criteria was also recorded.Data analysis was performed using, variance analysis test for repeated data Friedman, Mann-Whitney and T- Test. Good sedation of the 2 groups after intravenous administration was observed.In midazolam/propofol group BIS index was higher than ketamine/ propofol group but there was no statistical difference for sedation BIS index (PV=0.153). There was nostatistical difference for sedation score, working condition and recovery time between children receiving midazolam/ propofol or ketamine/ propofol (PV>0.05). Midazolam/ Propofol and Ketamine / Propofol, intravenous conscious sedation is efficacious forguiding the behavior of 4-6 years old children during dental treatment.
机译：尚无有关小儿牙齿镇静剂的临床试验。我们调查了在4-6岁的儿童中，使用咪达唑仑/丙泊酚与氯胺酮/丙泊酚相比，静脉内有意识镇静的疗效。在这项前瞻性临床试验中，研究了38例健康的非合作性在静脉有意识镇静下进行牙科治疗的儿童随机分为两组。一组使用咪达唑仑/异丙酚进行有意识的静脉镇静，另一组使用氯胺酮/异丙酚进行镇静。牙科镇静教师组（DSTG）的双谱指数和镇静分数由一名训练有素的盲人观察员评估每种方案的镇静效果。在治疗结束时，使用等级评定每个患者的工作条件还记录了达到DSA规模的标准，并记录了达到排放标准所需的时间。使用方差分析测试对重复数据Friedman，Mann-Whitney和T-Test进行了数据分析。静脉给药后两组镇静效果良好。咪达唑仑/异丙酚组的BIS指数高于氯胺酮/丙泊酚组，但镇静BIS指数无统计学差异（PV = 0.153）。咪达唑仑/丙泊酚或氯胺酮/丙泊酚的患儿镇静评分，工作条件和恢复时间无统计学差异（PV> 0.05）。咪达唑仑/丙泊酚和氯胺酮/丙泊酚，静脉有意识镇静可有效地规避4-6岁儿童在牙科治疗期间的行为。

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