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首页> 外文期刊>Indian Journal of Poultry Science >Impact of naked neck (Na) and frizzle (F) genes on general immunocompetence in egg type chicken.
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Impact of naked neck (Na) and frizzle (F) genes on general immunocompetence in egg type chicken.

机译：裸颈（Na）和毛躁（F）基因对蛋型鸡总体免疫能力的影响。

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Tropical oriented major genes Naked neck (Na) and Frizzle (F) were introgressed in two populations of White Leghorn at Central Avian Research Institute, Izatnagar (India). Major genes are believed to confer not only adaptability to the tropical climate, but also resistance to diseases. Disease resistance is composed of three basic sub-systems, the humeral, cellular and phagocytic. The humeral response is evaluated through antibody response to SRBCs, in vivo cell mediated (CMI) response to PHA-P. Total HA titre, 2-mercaptoethanol resistance (MER) and 2-mercaptoethanol sensitive (MES) antibody titre were estimated on 5 day post injection (dpi). Mean titres (log2) at 5 dpi for HA, MER and MES in Naked neck were 8.810+or-0279, 3.180+or-0.150, 5.630+or-0.269 and corresponding values for Frizzle were 8.429+or-0.279, 2.776+or-0.105, 5.653+or-0.269, respectively. There was no significant difference between varieties for the humoral immune response. CMI response to PHA-P was evaluated by injection of PHA-P into toe- web between second and third digit of chicks. The effective mean swelling measured after 24, 48 and 72 h post PHA-P injection in Naked neck and Frizzle varieties were 0.339+or-0.032, 0.097+or-0.031, 0.072+or-0.024 and 0.136+or-0.014, 0.091+or-0.017, 0.069+or-0.012 mm, respectively. CMI to PHP-A differed significantly (P<0.05) between two varieties and among time. CMIR observed at 24 h was statistically (P<0.05) higher in Naked neck than Frizzle. It was concluded that when all four immunocompetence traits were considered together, Naked neck was adjudged better than Frizzle. Introduction of Naked neck and Frizzle genes may be taken into consideration for improving disease resistance, particularly in tropical environment.
机译：在印度伊萨特纳加尔的中央鸟类研究所的两个白色来亨牛种群中，以热带为导向的主要基因裸颈（Na）和卷毛（F）渗入。据信主要基因不仅赋予对热带气候的适应性，而且还具有抗病性。抗病性由三个基本子系统组成，即肱骨，细胞和吞噬细胞。通过对SRBC的抗体反应，对PHA-P的体内细胞介导的（CMI）反应来评估肱骨反应。注射后5天（dpi）估计总HA滴度，2-巯基乙醇抗性（MER）和2-巯基乙醇敏感性（MES）抗体滴度。 5 dpi时，裸脖子上HA，MER和MES的平均滴度（log 2 ）为8.810+或-0279、3.180+或-0.150、5.630+或-0.269，相应的毛躁值为8.429 +或-0.279、2.776+或-0.105、5.653+或-0.269。体液免疫反应的品种之间没有显着差异。 CMI对PHA-P的反应是通过将PHA-P注射到第二到第三只小鸡脚趾之间的脚趾腹中来评估的。 PHA-P注射后24、48和72小时后，裸颈和卷毛品种的有效平均肿胀为0.339+或-0.032、0.097+或-0.031、0.072+或-0.024和0.136+或-0.014、0.091+或-0.017、0.069+或-0.012毫米。两个品种之间以及时间之间，CMI与PHP-A的差异显着（P <0.05）。在统计学上，在24小时观察到的CMIR在裸脖子上比Frizzle高（P <0.05）。结论是，当同时考虑所有四个免疫能力特质时，裸颈的判别率比Frizzle好。可以考虑引入裸颈和卷毛基因以提高抗病性，特别是在热带环境中。

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