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首页> 外文期刊>Brain research >Somatotopic reorganization in the brainstem and thalamus following peripheral nerve injury in adult primates.
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Somatotopic reorganization in the brainstem and thalamus following peripheral nerve injury in adult primates.

机译：成年灵长类动物周围神经损伤后脑干和丘脑的体位重组。

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摘要

Injury-induced reorganization of central somatotopic maps is a phenomenon that has proven to be useful for elucidating the mechanisms and time course of neural plasticity. To date, the overwhelming majority of this line of research has focused on such plastic events in cortical areas, at the expense of subcortical structures. In this study, we used multi-unit electrophysiological recording techniques to assess the somatotopic organization of brainstem and thalamic areas following chronic survival from paired median and ulnar nerve section in adult squirrel monkeys. We report that the extent of cutaneously-driven reorganization in both the cuneate nucleus of the brainstem and the ventroposterior lateral nucleus of the thalamus is comparable to that previously documented for area 3b of cortex. These observations are consistent with those previously reported in thalamus, and are unique for brainstem.
机译：损伤引起的中央体表重组是一种现象，已被证明有助于阐明神经可塑性的机制和时程。迄今为止，该研究领域的绝大多数都集中在皮质区域的此类塑性事件上，而以皮质下结构为代价。在这项研究中，我们使用多单位电生理记录技术来评估成年松鼠猴子中正中和尺神经对成对长期存活后脑干和丘脑区域的躯体组织。我们报告说，在脑干的楔形核和丘脑的腹后外侧核中，皮肤驱动的重组程度与先前记录的皮质区域3b相当。这些观察结果与先前在丘脑中报道的观察结果一致，并且对于脑干是独特的。

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