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首页> 外文期刊>Indian journal of pediatrics >Mortality and morbidity in extremely low birth weight (ELBW) infants in a neonatal intensive care unit
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Mortality and morbidity in extremely low birth weight (ELBW) infants in a neonatal intensive care unit

机译：新生儿重症监护病房的极低出生体重（ELBW）婴儿的死亡率和发病率

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Objective: To determine the morbidity and mortality in ELBW babies till discharge from a Neonatal Intensive Care Unit (NICU). Methods: This study was a prospective observational study conducted in a 40 bed well equipped level III care NICU between 01.12.2006 and 30.04.2008. All ELBW babies admitted during this period were assessed for morbidities and interventions required during NICU stay and for their outcome like survival or death. Results: The survival rate of 87 ELBW babies admitted during this period was 56.1 %. Pulmonary hemorrhage was the commonest cause of death (25 %) followed by respiratory distress syndrome (22.5 %), intraventricular hemorrhage (22.5 %) and sepsis (20 %). Significantly higher number of non-survivors were <750 g at birth (p = 0.0001) and <28 wk gestation (p = 0.0001). Small for gestational babies had better chances of survival compared to those appropriate for gestational age (p = 0.005). RDS (67.8 %), probable sepsis (62.1 %) and hyperbilirubinemia (59.8 %) were the most frequent morbidities. Conventional ventilation (72.4 %) and nasal CPAP(48.3 %) were the commonest respiratory interventions. Surfactant replacement therapy was required in 47.1 % babies. Conclusions: ELBW babies have a major contribution to mortality in a NICU. Babies with birth weight <750 g and gestation <28 wk have poor survival. RDS, pulmonary hemorrhage, IVH and sepsis are the common causes of death while RDS, sepsis and hyperbilirubinemia are the most common morbidities.
机译：目的：确定从新生儿重症监护病房（NICU）出院直至ELBW婴儿的发病率和死亡率。方法：这项研究是一项前瞻性观察性研究，在2006年1月12日至2008年4月30日之间，在40张床位，配备完善的III级护理重症监护病房中进行。对在此期间入院的所有ELBW婴儿进行了NICU住院期间所需的发病率和干预措施以及生存或死亡等结局的评估。结果：在此期间入院的87名ELBW婴儿的存活率为56.1％。肺出血是最常见的死亡原因（25％），其次是呼吸窘迫综合征（22.5％），脑室内出血（22.5％）和败血症（20％）。非存活者的数量明显更高，出生时小于750 g（p = 0.0001），妊娠小于28 wk（p = 0.0001）。与适合胎龄的婴儿相比，胎龄较小的婴儿有更好的生存机会（p = 0.005）。 RDS（67.8％），可能的败血症（62.1％）和高胆红素血症（59.8％）是最常见的发病率。常规通气（72.4％）和鼻CPAP（48.3％）是最常见的呼吸干预措施。 47.1％的婴儿需要使用表面活性剂替代疗法。结论：ELBW婴儿对重症监护病房的死亡率有重大贡献。出生体重<750 g和妊娠<28 wk的婴儿存活率较差。 RDS，肺出血，IVH和败血症是常见的死亡原因，而RDS，败血症和高胆红素血症是最常见的发病率。

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