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首页> 外文期刊>Brain research >Demonstration of expression of mRNA for particular AMPA and kainate receptor subunits in immature and mature cultured rat calvarial osteoblasts.
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Demonstration of expression of mRNA for particular AMPA and kainate receptor subunits in immature and mature cultured rat calvarial osteoblasts.

机译:证明了在未成熟和成熟培养的大鼠颅骨成骨细胞中特定AMPA和kainate受体亚基的mRNA表达。

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摘要

Reverse transcription polymerase chain reaction revealed expression of mRNA for particular subunits of ionotropic glutamate receptors (iGluR) in primary cultures of rat calvarial osteoblastic cells under immature to mature states. These included GluR3, KA1 and KA2 subunits, in addition to NR1 and NR2D subunits. These results suggest that glutamate may play an unidentified role in mechanisms associated with cellular development through particular subunits of iGluR in rat calvarial osteoblasts.
机译:逆转录聚合酶链反应揭示了在成熟状态下大鼠颅骨成骨细胞原代培养物中离子型谷氨酸受体(iGluR)特定亚基的mRNA表达。除了NR1和NR2D亚基外,这些还包括GluR3,KA1和KA2亚基。这些结果表明,谷氨酸可能在大鼠颅盖成骨细胞中通过iGluR的特定亚基在与细胞发育相关的机制中发挥未知作用。

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