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首页> 外文期刊>Indian medical journal >Outcome of Neonatal Bleeding in Rajendra Institute of Medical Sciences, Ranchi, Jharkhand
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Outcome of Neonatal Bleeding in Rajendra Institute of Medical Sciences, Ranchi, Jharkhand

机译：贾坎德邦兰契拉金德拉医学科学研究所新生儿出血的结果

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Neonalal haemorrhage either localised or generalized has significant morbidity and mortality. The identification of cause of bieeding is of paramount importance for the appropriate management and prognostication. The paucity of Indian studies on bleeding in newboras prompted us to do this study looking at aetiologicai factors, clinical features and the outcome.This prospective study was done in NICU of RIMS, Department of Paediatrics & Neonatology, Ranchi, between May 2012 to April 2013. A detailed history, family history, perinatal problems and thorough clinical assessment, relevant investigations were done when required, for all the 70 neonates who had bleeding manifestations out of 1826 admissions, during the same period. Immediate outcome i.e., survived or death and development assessment at 6 months of age in the survivors was done.The incidence of bleeding in neonates was 3.83%. VLBW babies (15.7%), preterm babies 0 2%) and out born babies (4.6%) had statistically significant risk of bleeding. 71.43% of neonates had bleedinfin the 1~(st) week of life. DIG constituted the major cause of bleeding (65.71%), septicaemia (11.43%) and VKDB constituted 7.4%. 2/3~(rd) cases of VKDB were classic VKDB. 10% of NICU deaths were in the neonates with bleeding. Bleeding constituted a significant risk factor for mortality in NICU. Out of 43 survivors, 30 cases were normal in neurodevelopment and physical outcome, 6 cases were lost to follow-up and developmental delay was noted in S cases. The outcome in the late VKDB was dismal (67% mortality and 33% neurologic sequelae). Preterm, IUGR, out born babies and sick neonates have higher incidence of bleeding. Bleeding is more common in the 1~(st) week of life. Late VKDB had bad prognosis. Vit. K prophylaxis has an important role in the prevention of VKDB.
机译：局部或全身性新生儿出血都有很高的发病率和死亡率。对于适当的管理和预后，识别出诱因是至关重要的。印度对新生婴儿出血的研究很少，这促使我们进行了病因学，临床特征和结局的研究。这项前瞻性研究于2012年5月至2013年4月在兰契市儿科和新生儿科RIMS的重症监护病房（NICU）中进行。详细的病史，家族史，围产期问题和全面的临床评估，并在需要时对同期内1826例入院的所有70例具有出血表现的新生儿进行了相关研究。立即评估结果，即幸存者在6个月大时的存活率或死亡和发育评估。新生儿出血的发生率为3.83％。 VLBW婴儿（15.7％），早产婴儿0 2％）和出生婴儿（4.6％）的出血风险有统计学意义。 71.43％的新生儿在出生后1周内有出血。 DIG是出血的主要原因（65.71％），败血病（11.43％），VKDB占7.4％。 VKDB的2/3〜（rd）个案例是经典VKDB。重症监护病房死亡的10％发生在有出血的新生儿中。出血是重症监护病房死亡率的重要危险因素。在43名幸存者中，有30例神经发育和身体预后正常，6例失去随访，S例发现发育迟缓。 VKDB晚期的结果令人沮丧（67％的死亡率和33％的神经系统后遗症）。早产，IUGR，外出婴儿和患病的新生儿出血的发生率较高。在生命的第一周（第一周），出血更为常见。晚期VKDB预后不良。维特预防钾对预防VKDB具有重要作用。

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