...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Brain research >Polycyclic neuromodulation of the feeding rhythm of the pond snail Lymnaea stagnalis by the intrinsic octopaminergic interneuron, OC.
【24h】

Polycyclic neuromodulation of the feeding rhythm of the pond snail Lymnaea stagnalis by the intrinsic octopaminergic interneuron, OC.

机译：内在的章鱼胺能中间神经元OC对池塘蜗牛Lymnaea stagnalis进食节律的多环神经调节。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We have examined the role of the octopamine-containing buccal OC interneuron in the fictive feeding rhythm generated by depolarizing a modulatory interneuron, SO, in the isolated central nervous system (CNS) of Lymnaea stagnalis. Before stimulating the SO, the initial fictive feeding rate was 2.0+/-0.37 bites/min (mean+/-S.E.). When the SO was stimulated, the fictive feeding rate more than doubled, increasing by 5.4+/-2.6 bites/min. Prestimulation of OC facilitates the ability of the modulatory neuron SO to drive fictive feeding 4 s later. Following OC stimulation, the increase in SO-driven feeding rate was 10.8+/-1.6 bites/min, significantly more than when only the SO was stimulated (P<0.02, paired t-test on five preparations). OC activity is not required during the SO stimulation for this enhancement. The maximum of the SO driven rhythm occurs between 6 and 12 s after the end of the OC stimulation at 20 bites/min. This is the maximum feeding rate of intact Lymnaea in sucrose. Facilitation is mimicked by bath applied octopamine at 5 microM. Facilitation is specific to OC interneurons, as the same prestimulation of the electrically coupled neuron N3P (central pattern generator) interneurons does not affect the feeding rhythm. The OC interneuron acts as a long term, polycyclic modulator, which peaks several feeding cycles after the OC activity.
机译：我们已经检查了含八足胺的颊OC中间神经元在虚构的哺乳节律中的作用，该假想的进食节奏是通过在分离的中生胸腺中枢神经系统（CNS）中对调节性中间神经SO进行去极化而产生的。在刺激SO之前，虚拟进料的初始速率为2.0 +/- 0.37比特/分钟（平均+/-标准误差）。当SO被刺激时，虚拟进料速率增加了一倍以上，增加了5.4 +/- 2.6咬/分钟。 OC的预刺激促进了调节神经元SO在4 s后驱动虚拟进食的能力。在OC刺激后，SO驱动的进食速率的增加为10.8 +/- 1.6比特/分钟，比仅刺激SO时显着增加（P <0.02，五种制剂的配对t检验）。在SO刺激过程中，不需要OC活性来增强这种功能。 SO驱动的节律的最大值出现在以20次/分钟的OC刺激结束后的6到12 s之间。这是完整的蔗糖中淋菌的最大进料速度。通过浴液施加5 microM的章鱼胺模拟促进作用。促进特定于OC中间神经元，因为电耦合神经元N3P（中央模式发生器）中间神经元的相同预刺激不会影响进食节奏。 OC中间神经元充当长期的多环调节剂，在OC活性后几个馈入周期达到峰值。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号