• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Infection >Serological and epidemiological analysis of an outbreak of gastroenteritis among military recruits in Germany caused by Cryptosporidium parvum.
【24h】

Serological and epidemiological analysis of an outbreak of gastroenteritis among military recruits in Germany caused by Cryptosporidium parvum.

机译：血清隐孢子虫引起的德国军人胃肠炎暴发的血清学和流行病学分析。

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Cryptosporidium spp. cause enteritic disease worldwide. Besides those patients with an impaired immune system, the general population is also at risk. PATIENTS AND METHODS: Stool samples from participants of a military field exercise were tested for enteritic pathogens and sera were analyzed for Cryptosporidium-antibodies. All participants received a questionnaire for assessing possible risk factors. RESULTS: After a 5-day field training, 201 of a total of 450 soldiers (45%) developed acute gastroenteritis. Immediate microbiological analysis ruled out enteropathogenic bacteria and viruses as the cause of the disease. Only after hospitalization of one of the patients diagnostic procedures were expanded to the identification of parasites and Cryptosporidium parvum was identified. In addition, 14 fecal samples of 217 specimens were subsequently identified in a Cryptosporidium antigen ELISA. A serological analysis of 214 sera revealed 72% positive for specific IgG antibodies compared with 17% of a control group of soldiers who had not participated in the field training (relative risk 3.38; 95% CI 2.39-4.77; p < 0.001). Analysis of specific IgM levels was less conclusive. Epidemiological analysis of questionnaires correlated drinking of tap water, or consumption of various meals with gastroenteritis. However, the source of contamination could not be identified. CONCLUSION: Cryptosporidium spp. can cause acute enteritis even in healthy, young adults as demonstrated by this outbreak. Using serological methods, the extent of the outbreak could be estimated in a retrospective analysis.
机译：背景：隐孢子虫属。在世界范围内引起肠道疾病。除了那些免疫系统受损的患者之外，普通人群也处于危险之中。患者和方法：对来自军事演习参与者的粪便样本进行了肠病原体检测，并对血清中的隐孢子虫抗体进行了分析。所有参与者都收到了一份问卷，用于评估可能的危险因素。结果：经过为期5天的野外训练，在450名士兵中，有201名（45％）患上了急性胃肠炎。立即的微生物学分析排除了致肠病的细菌和病毒是造成该疾病的原因。仅在其中一名患者入院后，诊断程序才扩展到寄生虫的鉴定，并鉴定出小隐隐孢子虫。此外，随后在隐孢子虫抗原ELISA中鉴定了217个标本的14个粪便样品。 214份血清的血清学分析显示，特异性IgG抗体阳性72％，而未参加野外训练的对照组的对照组为17％（相对风险3.38; 95％CI 2.39-4.77; p <0.001）。对特定IgM水平的分析尚无定论。问卷的流行病学分析表明，饮用自来水或食用各种食物与肠胃炎相关。但是，无法确定污染源。结论：隐孢子虫属。如这次爆发所表明的，即使在健康的年轻人中也可引起急性肠炎。使用血清学方法，可以在回顾性分析中估计爆发的程度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号