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Risk factors for hospital-acquired urinary tract infection in a large English teaching hospital: a case-control study.

机译:一家大型英语教学医院中医院获得性尿路感染的危险因素:病例对照研究。

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About 10% of patients in hospital develop a hospital-acquired infection (HAI); the most commonly affected site is the urinary tract. Many studies have examined risk factors for HAI but few have adjusted for confounding and interaction. We performed a prospective case-control study on six acute wards of a busy English teaching hospital to assess risk factors for hospital-acquired urinary tract infection (HAUTI). Over a 2-year period, 136 cases were identified (2.8% of all patient episodes) along with 408 controls. Multiple logistic regression revealed that female sex, increased length of stay, elective admission, surgical operation, and transurethral and repeated intermittent catheterization were all significant independent risk factors for HAUTI. However, specialty of admission was also a significant risk factor when added to the model and, under these conditions, only length of stay and catheterization also remained significant. We detected significant interactions suggesting that the risk of HAUTI is maximal among women undergoing elective surgery, especially those who are catheterized; however, the overall risk of HAUTI among patients admitted electively was greater than for patients admitted as emergencies.
机译:医院中约有10%的患者会发生医院获得性感染(HAI);最常受累的部位是尿路。许多研究检查了HAI的危险因素,但很少针对混杂因素和相互作用进行调整。我们在一家繁忙的英语教学医院的六个急性病房进行了一项前瞻性病例对照研究,以评估医院获得性尿路感染(HAUTI)的危险因素。在2年的时间里,共发现136例病例(占所有患者发作的2.8%)以及408例对照。多元logistic回归显示,女性,住院天数增加,择期入院,外科手术以及经尿道和反复间歇性导尿均是HAUTI的重要独立危险因素。但是,入院时的专业性也是添加到模型中的重要危险因素,在这种情况下,仅住院时间和导管插入术仍然很重要。我们检测到显着的相互作用,表明接受择期手术的妇女,尤其是经导管的妇女,HAUTI的风险最大。但是,选择性入院患者中发生HAUTI的总体风险要高于急诊患者。

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