A case of aortic valve disease associated with Tropheryma whippelii infection in the absence of other signs of Whipple's disease.

Geissdorfer W; Wittmann I; Seitz G; Cesnjevar R; Rollinghoff M; Schoerner C; Bogdan C

首页> 外文期刊>Infection >A case of aortic valve disease associated with Tropheryma whippelii infection in the absence of other signs of Whipple's disease.

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A case of aortic valve disease associated with Tropheryma whippelii infection in the absence of other signs of Whipple's disease.

机译：在没有其他Whipple's病征象的情况下，主动脉瓣膜疾病伴whippelii感染。

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A case of endocarditis caused by Tropheryma whippelii is reported. The 69-year-old patient was diagnosed as suffering from severe aortic regurgitation requiring aortic valve replacement, but showed no other symptoms of Whipple's disease. T. whippelii was detected in the explanted aortic valve by broad-range PCR amplification of the 16S rDNA and subsequent sequence analysis of the product. The etiologic agent was classified as a type 2A sequence variant based on the 16S-23S intergenic spacer and the 23S rDNA (domain III) sequences. The histological examination of the aortic valve was compatible with Whipple's disease. A duodenal biopsy revealed an infection with Giardia lamblia, but T. whippelii and histological signs of Whipple's disease were not detectable.

机译：据报道有一例由特发性疟原虫引起的心内膜炎。这位69岁的患者被诊断患有严重的主动脉瓣反流，需要更换主动脉瓣，但未显示出其他Whipple病症状。通过16S rDNA的宽范围PCR扩增和随后的产物序列分析，在外主动脉瓣中检测到了鞭状T. whippelii。根据16S-23S基因间隔区和23S rDNA（结构域III）序列，病原体被分类为2A型序列变体。主动脉瓣的组织学检查符合Whipple病。十二指肠活检显示有兰氏贾第鞭毛虫感染，但未检出惠氏鞭毛虫和Whipple病的组织学迹象。

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来源
《Infection》 |2001年第1期|共4页
作者
Geissdorfer W; Wittmann I; Seitz G; Cesnjevar R; Rollinghoff M; Schoerner C; Bogdan C;
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正文语种 eng
中图分类传染病;
关键词
Actinobacteria Group; Actinomycetales Infections; Endocarditis; Bacterial; 放线菌族; 放线菌目感染; 心内膜炎; 细菌性; Whipple病;

机译：Actinobacteria Group;Actinomycetales Infections;Endocarditis;Bacterial;放线菌族;放线菌目感染;心内膜炎;细菌性;Whipple病;

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专利

1. A case of aortic valve disease associated with Tropheryma whippelii infection in the absence of other signs of Whipple's disease. [J] . Geissdorfer W, Wittmann I, Seitz G, Infection . 2001,第1期

机译：在没有其他Whipple's病征象的情况下，主动脉瓣膜疾病伴whippelii感染。
2. Localization of Tropheryma whippelii rRNA in tissues from patients with Whipple's disease. [J] . Fredricks DN, Relman DA The Journal of Infectious Diseases . 2001,第8期

机译：Whipple's病患者组织中的营养丰富的乳白质rRNA的定位。
3. Culture and immunological detection of Tropheryma whippelii from the duodenum of a patient with Whipple disease. [J] . Raoult D, La-Scola B, Lecocq P, JAMA: the Journal of the American Medical Association . 2001,第8期

机译：患有Whipple病患者十二指肠的鞭毛螺旋体的培养和免疫学检测。
4. Statins in Calcific Aortic Valve Disease: From Bench to BedsideDesigning Clinical Trials in Aortic Valve Disease: From Bench to Bedside [C] . Rajamannan Nalini M. Moura Luis M. World Congress on Heart Disese-International Academy of Cardiology Annual Scientific Session 2010 . 2010

机译：钙化主动脉瓣病的他汀类药物：从长凳到主动脉瓣病的临床试验：从长凳到床边
5. Improved Models to Understand the Sequence of Events in Early Calcific Aortic Valve Disease. [D] . Porras, Ana Maria. 2016

机译：改进的模型，以了解早期钙化主动脉瓣疾病的事件顺序。
6. Coinfection with Tropheryma whippelii and a Whipples disease-associated bacterial organism detected in a patient with central nervous system Whipples disease. [O] . K Neumann, V Neumann, S Zierz, 1997

机译：在患有中枢神经系统Whipples病的患者中检测到与Troippyma whippelii和Whipples疾病相关的细菌共感染。
7. Tropheryma whipplei aortic valve endocarditis without systemic Whipple's disease [O] . Chan Vincent, Wang Bing, Veinot John P., 2011

机译：无系统性Whipple病的特发性惠比氏主动脉瓣膜心内膜炎

A case of aortic valve disease associated with Tropheryma whippelii infection in the absence of other signs of Whipple's disease.

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