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The clinical diagnosis of severe viral influenza a.

机译:严重病毒性流感的临床诊断a。

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I read with interest the article by Hoeven et al. describing discrepancies between the results of influenza testing and the clinical diagnosis of influenza. The authors point out that infection control measures should be based on influenza testing and not clinical findings .From an infection control perspective, initial containment measures of viral influenza should be based on influenza testing particularly in those mildly to moderately ill which are difficult to diagnose clinically. There is also great variability among the various techniques used to diagnose influenza from respiratory secretions [2-5]. During 2006-2007 influenza season, we too experienced discrepancies between rapid antigen testing and direct fluoursecent antibody (DFA) testing for influenza. Given the variability in sensitivity/specificity with different influenza diagnostic tests, laboratory testing, rather than clinical assessment, is the basis for influenza containment measures.The difficulty in diagnosing influenza clinically depends upon the severity of the illness. The reason, it is not possible to differentiate mild/moderate influenza from influenza-like illnesses (ILIs) due to parainfluenza virus, respiratory synsycial virus (RSV), adenovirus, etc., is because the clinical presentation is non-specific .
机译:我感兴趣地阅读了Hoeven等人的文章。描述流感检测结果与流感临床诊断之间的差异。作者指出,感染控制措施应基于流感检测而非临床发现。从感染控制的角度来看,病毒性流感的初始遏制措施应基于流感检测,尤其是对于那些在临床上难以诊断的轻度至中度疾病。从呼吸道分泌物诊断流感的各种技术之间也存在很大差异[2-5]。在2006-2007年的流感季节,我们也经历了快速抗原检测与流感直接荧光抗体(DFA)检测之间的差异。鉴于不同的流感诊断测试的敏感性/特异性存在差异,因此实验室遏制措施而不是临床评估是流感遏制措施的基础。临床诊断流感的难度取决于疾病的严重程度。之所以无法将副流感病毒,呼吸道合胞病毒(RSV),腺病毒等引起的轻度/中度流感与类流感疾病(ILI)区分开来是因为临床表现是非特异性的。

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