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首页> 外文期刊>Infection control and hospital epidemiology >Reduction of seasonal influenza transmission among healthcare workers in an intensive care unit: a 4-year intervention study in Thailand.
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Reduction of seasonal influenza transmission among healthcare workers in an intensive care unit: a 4-year intervention study in Thailand.

机译：减少重症监护病房中医护人员的季节性流感传播：泰国的一项为期4年的干预研究。

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OBJECTIVE: To evaluate the feasibility and effectiveness of an influenza control bundle to minimize healthcare-associated seasonal influenza transmission among healthcare workers (HCWs) in an intensive care unit (ICU) equipped with central air conditioning.METHODS: A quasi-experimental study was conducted in a 500-bed tertiary care center in Thailand from July 1, 2005, through June 30,2009. The medical ICU (MICU) implemented an influenza control bundle including healthcare worker (HCW) education, influenza screening of adult community-acquired pneumonia patients, antiviral treatment of patients and ill HCWs who tested positive for influenza, promotion of influenza vaccination among HCWs, and reinforcement of standard infection control policies. The surgical ICU (SICU) and coronary care unit (CCU) received no intervention.RESULTS: The numbers of influenza infections among HCWs during the pre- and postintervention periods were 18 cases in 5,294 HCW days and 0 cases in 5,336 HCW-days in the MICU (3.4 vs 0 cases per 1,000 HCW-days; P ! .001), 19 cases in 4,318 HCW-days and 20 cases in 4,348 HCW-days in the SICU (4.4 vs 4.6 cases per 1,000 HCW-days; Pp.80), and 18 cases in 5,000 HCW-days and 18 cases in 5,143 HCW-days in the CCU (3.6 vs 3.5 cases per 1,000 HCW-days; Pp.92), respectively. Outbreak-related influenza occurred in 7 MICUHCWs, 6 SICU HCWs, and 4 CCU HCWs before intervention and 0 MICU HCWs, 9 SICU HCWs, and 8 CCU HCWs after intervention.Before and after intervention, 25 (71%) and 35 (100%) of 35 MICU HCWs were vaccinated, respectively (P ! .001); HCW vaccination coverage did not change significantly in the SICU (21 [70%] of 30 vs 24 [80%] of 30; Pp.89) and CCU (19 [68%] of 28 vs 21 [75%]of 28; Pp.83). The estimated costs of US Dollars 6,471 per unit for postintervention outbreak investigations exceeded the intervention costs of US Dollars 4,969.CONCLUSION: A sustained influenza intervention bundle was associated with clinical and economic benefits to a Thai hospital.
机译：目的：评估在一个配备中央空调的重症监护病房（ICU）中，控制流感捆绑以最大程度地减少医护人员与季节性流感之间传播的可行性和有效性。方法：进行了一项半实验研究从2005年7月1日至2009年6月30日在泰国拥有500个床位的三级护理中心。医疗ICU（MICU）实施了流感控制捆绑，包括医护人员（HCW）教育，对成年社区获得性肺炎患者进行流感筛查，对流感检测呈阳性的患者和患病的HCW进行抗病毒治疗，在HCW中促进流感疫苗接种以及加强标准的感染控制政策。结果：干预前和干预后HCW的感染人数分别为5 294 HCW天的18例和5 336 HCW天的0例。 MICU（每1000 HCW天3.4例0例; P！.001），SICU中4,318 HCW天19例和4348 HCW天20例（每1000 HCW天4.4例4.6例; Pp.80 ），以及CCU中每5,000 HCW天的18例和5,143 HCW天的18例（每1000 HCW天分别为3.6和3.5例; Pp.92）。干预前有7例MICUHCW，6例SICU HCW和4例CCU HCW与暴发相关的流感发生，干预前后25例（71％）和35例（100％）发生了0例MICU HCW，9例SICU HCW和8例CCU HCW。 ）分别对35例MICU HCW进行了疫苗接种（P！.001）; SICU（30中的21 [70％]比30中的24 [80％]; Pp.89）和CCU（28中的19 [68％]对28中的21 [75％]）中的HCW疫苗接种率没有显着变化。第83页）。干预后暴发调查的每单位估计成本为6,471美元，超过了4,969美元的干预成本。结论：持续的流感干预捆绑与泰国医院的临床和经济收益相关。

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