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首页> 外文期刊>Brain research. Brain research protocols >A new method for the assessment of spatial orientation and spatial anxiety in mice.
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A new method for the assessment of spatial orientation and spatial anxiety in mice.

机译：一种评估小鼠空间定向和空间焦虑的新方法。

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The implication of integrated functional sensory relations of the body to space in anxiety disorders is a very important issue which encourages the development of animal models, in particular, for pharmacological perspectives and for the functional assessment of the deficits induced by genetic manipulation in the mouse or the rat. A new experimental device is presented here: It is comprised of a rotating tunnel and a rotating-beam controlled by computer which can be used for multiple visuo-idiothetic and kinesthetic sensory conflict situations during active locomotor behaviour by mice. The system is linked to a digital video system, Video-Track trade mark, designed to track and record the movements of the animals. Anxious BALB/cByJ mice were compared to non-anxious C57BL/6J mice and were seen to display highly disturbed locomotor behaviour in a sensory conflict situation. The model highlights the advantages of video-digital analysis for animal behavioural sciences.
机译：焦虑症中机体与空间的综合功能感官关系的涵义是一个非常重要的问题，它鼓励动物模型的发展，尤其是从药理学角度以及对小鼠或小鼠遗传操纵所致缺陷的功能评估方面那只老鼠。这里介绍了一种新的实验设备：它由旋转隧道和计算机控制的旋转光束组成，可在小鼠主动运动行为期间用于多种视觉-惯性和动觉的感觉冲突情况。该系统链接到旨在跟踪和记录动物运动的数字视频系统Video-Track商标。将焦虑的BALB / cByJ小鼠与非焦虑的C57BL / 6J小鼠进行了比较，发现它们在感觉冲突情况下显示出高度干扰的运动行为。该模型突出了视频数字分析对动物行为科学的优势。

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