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首页> 外文期刊>Brain research. Brain research protocols >EEG-dependent ERP recording: using TMS to increase the incidence of a selected pre-stimulus pattern.
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EEG-dependent ERP recording: using TMS to increase the incidence of a selected pre-stimulus pattern.

机译：EEG依赖的ERP记录：使用TMS增加选定的刺激前模式的发生率。

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摘要

EEG dependent event-related potential (ERP) recording (interactive ERP) is an extension to ERP paradigms whereby stimuli are initiated in response to a selected pattern of background EEG. This form of recording is critically dependent upon the incidence of the particular pattern of interest. We introduce here a process that modifies the EEG in a predictable manner so as to increase the incidence of a particular pattern. Transcranial magnetic stimulation (TMS) stimuli are applied in response to a selected pattern of pre-TMS activity, and the post-TMS response is characterized by the incidence of a defined pattern of EEG activity. Analysis of validation test results obtained with the TMS modification part of the process verifies an increased incidence of the response pattern after TMS stimuli, compared with placebo stimuli. The TMS modification procedure is then combined with interactive ERP recording in a two step process to affect the ERP response to sensory stimuli. The post-TMS pattern from the firststep becomes the pre-stimulus pattern of the interactive ERP recording in the second step. The TMS modified interactive ERP (TMIERP) process is illustrated here using an auditory oddball paradigm. The amplitude of the P300 peak obtained using this process was significantly higher than that obtained using the standard auditory oddball paradigm.
机译：依赖于EEG的事件相关电位（ERP）记录（交互式ERP）是对ERP范式的扩展，由此可以响应于选定的背景EEG模式而启动刺激。这种记录形式主要取决于特定感兴趣模式的发生率。我们在这里介绍一种以可预测的方式修改脑电图的过程，以增加特定模式的发生率。经颅磁刺激（TMS）刺激可响应选定的TMS前活动模式而应用，TMS后反应的特征在于脑电活动定义模式的发生。与安慰剂刺激相比，使用TMS修饰过程的一部分验证测试结果进行的分析验证了TMS刺激后反应模式的发生率增加。然后，在两步过程中将TMS修改过程与交互式ERP记录相结合，以影响ERP对感觉刺激的反应。从第一步开始的后TMS模式成为第二步中交互式ERP记录的刺激前模式。 TMS修改后的交互式ERP（TMIERP）流程在此使用听觉奇异球范例进行了说明。使用此过程获得的P300峰的幅度明显高于使用标准听觉奇异球范例获得的P300峰的幅度。

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