Role of granulocyteeutrophil transfusions for haematology/oncology patients in the modern era

StraussR.G.

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Role of granulocyteeutrophil transfusions for haematology/oncology patients in the modern era

机译：粒细胞/中性粒细胞输注在现代血液学/肿瘤学患者中的作用

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Infections continue to be a serious problem for severely neutropenic oncology and haematopoietic progenitor cell (HPC) transplant patients. Although it is now possible to collect much larger numbers of neutrophils (PMNs) from donors stimulated with granulocyte colony-stimulating factor + corticosteroids, the efficacy of these 'modern' granulocyte/PMN transfusions, with higher doses of PMNs, has not been established by convincing randomized control trials. Accordingly, they cannot be recommended for standard therapy at this time.

机译：对于严重的中性粒细胞减少的肿瘤和造血祖细胞（HPC）移植患者，感染仍然是一个严重的问题。尽管现在有可能从粒细胞集落刺激因子+皮质类固醇刺激的供体中收集到大量嗜中性粒细胞（PMN），但这些“现代”粒细胞/ PMN输注与更高剂量的PMN的疗效尚未得到证实。令人信服的随机对照试验。因此，目前不建议将它们用于标准疗法。

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来源
《British Journal of Haematology》 |2012年第3期|共8页
作者
StraussR.G.;
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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
关键词
Granulocyte transfusions; Granulocyte-colony stimulating factor; Neutropenic infections; Neutrophil transfusions; Transfusions;

机译：粒细胞输注;粒细胞集落刺激因子;中性粒细胞减少感染;中性粒细胞输注;输血;

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1. Role of granulocyteeutrophil transfusions for haematology/oncology patients in the modern era [J] . StraussR.G. British Journal of Haematology . 2012,第3期

机译：粒细胞/中性粒细胞输注在现代血液学/肿瘤学患者中的作用
2. New strategies in the treatment of infectious complications in haematology and oncology: is there a role for out-patient antibiotic treatment of febrile neutropenia? [J] . Karthaus M, Carratala J, Jurgens H, Chemotherapy: International Journal of Experimental and Clinical Chemotherapy . 1998,第6期

机译：血液学和肿瘤学中传染性并发症治疗的新策略：门诊抗生素治疗高热性中性粒细胞减少症有作用吗？
3. Central venous catheter-related Stenotrophomonas maltophilia bacteraemia and associated relapsing bacteraemia in haematology and oncology patients. [J] . Lai CH, Wong WW, Chin C, Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases . 2006,第10期

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7. Central venous catheter-related Stenotrophomonas maltophilia bacteraemia and associated relapsing bacteraemia in haematology and oncology patients [O] . Lai C.-H., Wong W.-W., Chin C., 2006

机译：血液和肿瘤科患者中与中心静脉导管相关的嗜麦芽窄食单胞菌嗜麦芽杆菌血症和相关复发性菌血症

Role of granulocyteeutrophil transfusions for haematology/oncology patients in the modern era

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