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首页> 外文期刊>British Journal of Haematology >Autologous stem cell transplantation remains beneficial for patients relapsing after R-CHOP chemotherapy and who respond to salvage chemotherapy.
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Autologous stem cell transplantation remains beneficial for patients relapsing after R-CHOP chemotherapy and who respond to salvage chemotherapy.

机译:自体干细胞移植对于R-CHOP化疗后复发且对挽救性化疗有反应的患者仍然有益。

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摘要

The initial results of the Collaborative Trial in Relapsed Aggressive Lymphoma (CORAL) study have recently been reported (Gisselbrecht et al, 2010). This study focused on the comparison of R-DHAP (dexamethasone, cytarabine, cisplatin, rituximab) versus R-ICE (ifosfamide, carboplatin, etoposide, rituximab) salvage chemotherapy in patients with diffuse large B cell lymphoma (DLBCL) in first relapse or refractory to first-line chemotherapy. Patients who achieved a complete (CR) or partial response (PR) went on to autologous stem cell transplantation (ASCT).
机译:最近已经报道了在复发性侵袭性淋巴瘤(CORAL)研究中进行的合作试验的初步结果(Gisselbrecht等,2010)。这项研究的重点是在初次复发或难治性弥漫性大B细胞淋巴瘤(DLBCL)患者中,R-DHAP(地塞米松,阿糖胞苷,顺铂,利妥昔单抗)与R-ICE(异环磷酰胺,卡铂,依托泊苷,利妥昔单抗)抢救化疗的比较进行一线化疗。达到完全缓解(CR)或部分缓解(PR)的患者继续进行自体干细胞移植(ASCT)。

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