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Emulsion compositions for polyfunc-tional active ingredients

机译:用于多功能活性成分的乳液组合物

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摘要

Structured lipids are the basis for this patent.An oil phase made from structured tri-acylglycerols containing long-chain fatty acids (and free from C-6 to C-12 fatty acids) is emulsified with an aqueous phase and an emulsi-fier to produce pharmaceutical-quality oil-in-water emulsions for delivery of poly-functional active ingredients.The present invention also provides methods of treating an animal with a polyfunctional active ingredient,using dosage forms of the pharmaceutical emulsions.Benefits in use include reduced irritation and local toxicity at the site of administration,reduced drug precipitation on injection,and enhanced emulsion stability.
机译:结构化脂质是该专利的基础。将由含有长链脂肪酸(不含C-6至C-12脂肪酸)的结构化三酰基甘油制得的油相与水相一起乳化,并制成乳化剂。生产用于递送多官能活性成分的药物品质的水包油乳剂。本发明还提供了使用多官能活性成分的剂型的药物乳剂治疗动物的方法。使用的益处包括减少刺激性和给药部位的局部毒性,减少了注射时的药物沉淀,增强了乳剂的稳定性。

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