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首页> 外文期刊>Integrative cancer therapies >Altered circadian rhythms and cancer-related fatigue outcomes.
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Altered circadian rhythms and cancer-related fatigue outcomes.

机译：昼夜节律改变和癌症相关的疲劳结果。

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摘要

Fatigue is one of the most frequent and distressing complaints reported by patients with cancer. Describing relationships among disrupted circadian rhythms and cancer-related fatigue is important to the design and testing of interventions that target specific underlying etiology of fatigue. The purpose of this article is to review the literature on whether evidence exists to support the notion that disrupted circadian rhythms provide a mechanism of cancer-related fatigue. Searches were conducted from January 1950 to January 2010, to locate pertinent articles using 4 electronic databases: PubMed, MEDLINE, CINAHL, and Scopus. RESULTS: After reviewing the articles, 15 were selected as meeting the established criteria of the study and were critiqued. Statistical approaches varied across studies, which may influence generalizability of results. Although commonalities across studies did emerge, there was a lack of consistency in variables studied, and most studies did not identify a theoretical framework. More research needs to be conducted using consistent types and characteristics of disrupted circadian rhythms in relation to fatigue, including temporal relationships between circadian rhythms, fatigue, and cancer.
机译：疲劳是癌症患者报告的最常见且令人困扰的抱怨之一。昼夜节律紊乱与癌症相关的疲劳之间的关系，对于针对特定疲劳潜在病因的干预措施的设计和测试至关重要。本文的目的是回顾有关是否存在证据支持昼夜节律紊乱提供癌症相关疲劳机制这一观点的文献。搜索从1950年1月到2010年1月进行，以使用4个电子数据库（PubMed，MEDLINE，CINAHL和Scopus）查找相关文章。结果：在对文章进行审查后，选择了15项符合研究的既定标准并进行了评论。不同研究之间的统计方法不同，这可能会影响结果的概括性。尽管确实出现了研究之间的共性，但是所研究的变量缺乏一致性，而且大多数研究都没有确定理论框架。需要使用与疲劳有关的连续性昼夜节律的类型和特征进行更多的研究，包括昼夜节律，疲劳和癌症之间的时间关系。

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