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Staphylococci and implant surfaces: a review.

机译:葡萄球菌和植入物表面:综述。

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摘要

Surfaces of internal fracture fixation implants are generally designed to encourage soft- and/or hard-tissue adherence, eventually leading to tissue or osseo integration. Unfortunately, this feature may also encourage bacterial adhesion. About half of the two million cases of nosocomial infections per year in the US are associated with indwelling devices. In the UK, implant-associated infections are estimated to cost pound 7-11 million per year, and with the rise in antibiotic-resistant bacteria, are an important issue. Soft-tissue infections and osteomyelitis are serious complications associated with implants, particularly open fractures, external fixation devices, and intramedullary nailing. Consequences of implant-associated infections include prolonged hospitalization with systemic antibiotic therapy, several revision procedures, possible amputation, and even death. This review discusses the issue of implant-associated infections and some of the methods used to prevent bacterial adhesion to osteosynthesis implants.
机译:内部骨折固定植入物的表面通常设计成促进软组织和/或硬组织的粘附,最终导致组织或骨整合。不幸的是,此功能还可能促进细菌粘附。在美国,每年200万例医院感染病例中,约有一半与留置装置有关。在英国,与植入物相关的感染估计每年花费7-11百万英镑,并且随着抗生素抗性细菌的增加,这是一个重要的问题。软组织感染和骨髓炎是与植入物相关的严重并发症,特别是开放性骨折,外固定装置和髓内钉。植入物相关感染的后果包括长期使用全身性抗生素治疗的住院时间,多次翻修程序,可能的截肢甚至死亡。这篇综述讨论了植入物相关感染的问题以及一些用于防止细菌粘附于骨合成植入物的方法。

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