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Pelvic trauma: What are the predictors of mortality and cardiac, venous thrombo-embolic and infectious complications following injury?

机译:骨盆创伤:损伤后死亡率以及心脏,静脉血栓栓塞和感染并发症的预测因素是什么?

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Introduction This study sought to determine risk factors that influence mortality, cardiac events, venous thrombo-embolic disease (VTED), and infection following fractures of the pelvis and/or acetabulum. Methods The 2008 National Sample Program (NSP) of the National Trauma Databank was queried to identify all patients who sustained pelvic and acetabular fractures. Demographic data, injury-specific and surgical characteristics, and medical co-morbidities were abstracted. The occurrence of in-hospital mortality, cardiac events, VTED and infections were documented. Univariate testing, weighted logistic regression, and sensitivity analyses were performed to identify significant independent predictors of mortality and the complications under study. Results The NSP contained 41,297 cases of pelvic trauma. In-hospital mortality was documented in 3055 (7%) and one or more complications occurred in 6932 (17%). Cardiac events transpired in 2% of patients, VTED in 4% and infections in 3%. Increasing age, shock, time to procedure, ISS, and GCS were predictive of mortality. Cardiac events were found to be influenced by obesity, diabetes, ISS, GCS, age, and trauma mechanism. VTED was impacted by obesity, history of respiratory disease, male sex, ISS, GCS, medical co-morbidities, and time to procedure. Injuries caused by mechanisms other than blunt trauma, shock, age, ISS, GCS, medical co-morbidities, and time to procedure were associated with infection. Conclusions Several important predictors were identified for specific complications and mortality following pelvic trauma. The design of this study may render it more generalisable to American patients with pelvic injuries. Level of evidence II - Prognostic retrospective study of a prospective dataset.
机译:引言这项研究试图确定影响骨盆和/或髋臼骨折后的死亡率,心脏事件,静脉血栓栓塞性疾病(VTED)和感染的危险因素。方法询问国家创伤数据库的2008年国家样本计划(NSP),以鉴定所有患有骨盆和髋臼骨折的患者。人口统计数据,特定于损伤和外科手术的特征,以及医学上的合并症被抽象出来。记录了院内死亡率,心脏事件,VTED和感染的发生。进行了单变量测试,加权逻辑回归和敏感性分析,以确定死亡率和所研究并发症的重要独立预测因子。结果NSP合并盆腔创伤41297例。 3055(7%)的住院死亡率被记录,6932(17%)发生的一种或多种并发症。 2%的患者发生心脏事件,4%的患者发生VTED,3%的患者发生感染。年龄增加,休克,手术时间,ISS和GCS可以预测死亡率。发现心脏事件受肥胖,糖尿病,ISS,GCS,年龄和创伤机制的影响。 VTED受肥胖,呼吸系统疾病史,男性,ISS,GCS,医学合并症和手术时间的影响。由钝性外伤,休克,年龄,ISS,GCS,医学合并症和手术时间以外的机制造成的伤害与感染有关。结论确定了骨盆创伤后特定并发症和死亡率的几个重要预测因素。这项研究的设计可能使其对美国骨盆损伤患者更具普遍性。证据水平II-前瞻性数据集的预后回顾性研究。

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