Diagnosis and management of acquired coagulation inhibitors: A guideline from UKHCDO

WCollinsP.; ChalmersE.; HartD.; JenningsI.; LiesnerR.; RangarajanS.; TalksK.; WilliamsM.; R.M.HayC.

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Diagnosis and management of acquired coagulation inhibitors: A guideline from UKHCDO

机译：获得性凝血抑制剂的诊断和管理：UKHCDO的指南

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Acquired coagulation inhibitors result from immune-mediated depletion or inhibition of a coagulation factor. Inhibitors are most commonly directed against factor VIII (FVIII) and von Willebrand factor (VWF) and inhibitors against other coagulation factors are only occasionally reported. Since the publication of previous guidelines (Laffan et al, 2004; Pasi et al, 2004; Hay et al, 2006) substantial new data has been published on acquired FVIII inhibitors, necessitating updated guidelines.

机译：获得性凝血抑制剂是由于免疫介导的耗竭或凝血因子的抑制而产生的。抑制剂最常见的是针对凝血因子VIII（FVIII）和von Willebrand因子（VWF）的药物，仅偶尔报道了针对其他凝血因子的抑制剂。自从先前的指南发布（Laffan等，2004; Pasi等，2004; Hay等，2006）以来，关于已获得的FVIII抑制剂的大量新数据已经发布，因此需要更新指南。

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来源
《British Journal of Haematology》 |2013年第6期|共16页
作者
WCollinsP.; ChalmersE.; HartD.; JenningsI.; LiesnerR.; RangarajanS.; TalksK.; WilliamsM.; R.M.HayC.;
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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
关键词
Acquired; Autoimmune; Coagulation factor; Factor VIII; Inhibitor;

机译：获得性;自身免疫;凝血因子;因子VIII;抑制剂;

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机译：获得性凝血抑制剂的诊断和管理：UKHCDO的指南
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Diagnosis and management of acquired coagulation inhibitors: A guideline from UKHCDO

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