Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures.

Masumizu T; Noda Y; Mori A; Packer L

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Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures.

机译：海藻酸盐诱发癫痫发作期间和之后，小鼠海马切片中抗坏血酸基团的电子自旋共振分析。

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As an index of oxidative status, we analyzed ascorbyl radical generation during and after kainate-induced seizures in mouse hippocampus, using an ESR spectrometer equipped with a special tissue-type quartz cell. A specific doublet ESR spectrum was observed after seizures, and the g value and the hyperfine coupling constant (hfcc) of the spectrum were identical with those of ascorbyl radical itself. Antiepileptic zonisamide inhibited the generation of ascorbyl radical accompanying the seizures.

机译：作为氧化状态的指标，我们使用配备有特殊组织型石英电池的ESR光谱仪分析了海藻酸盐诱发的小鼠海马癫痫发作期间和之后的抗坏血酸自由基的产生。癫痫发作后观察到特定的双峰ESR光谱，该光谱的g值和超精细偶合常数（hfcc）与抗坏血酸基团本身相同。抗癫痫药唑尼沙胺可抑制癫痫发作时抗坏血酸基的产生。

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《Brain research. Brain research protocols》 |2005年第3期|共5页
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Masumizu T; Noda Y; Mori A; Packer L;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Ascorbic Acid; Excitatory Amino Acid Agonists; Free Radicals; Hippocampus; 抗坏血酸; 兴奋性氨基酸激动剂; 自由基; 海马; 红藻氨酸; 发作;

机译：Ascorbic Acid;Excitatory Amino Acid Agonists;Free Radicals;Hippocampus;抗坏血酸;兴奋性氨基酸激动剂;自由基;海马;红藻氨酸;发作;

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1. Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures. [J] . Masumizu T, Noda Y, Mori A, Brain research. Brain research protocols . 2005,第1a3期

机译：海藻酸盐诱发癫痫发作期间和之后，小鼠海马切片中抗坏血酸基团的电子自旋共振分析。
2. An electron spin resonance study for real-time detection of ascorbyl free radicals after addition of dimethyl sulfoxide in murine hippocampus or plasma during kainic acid-induced seizures. [J] . Matsumoto S, Shingu C, Koga H, Neurochemical research . 2010,第7期

机译：电子自旋共振研究，用于在海藻酸诱导的癫痫发作期间在鼠海马或血浆中添加二甲亚砜后实时检测抗坏血酸自由基。
3. Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. II. The ascorbyl radical [J] . N J Dodd, J M Giron-Conland British Journal of Cancer . 1975,第4期

机译：电子自旋共振研究小鼠骨髓性白血病发展过程中的变化。二。抗坏血酸基
4. Electron Spin Resonance Study of Conventional Radical Polymerization of tert-Butyl Methacrylates Using Radical Precursors Prepared by Atom Transfer Radical Polymerization [C] . Atsushi Kajiwara, Mikiharu Kamachi, American Chemical Society, American Chemical Society symposium on advances in controlled/living radical polymerization . 2003

机译：采用原子转移自由基聚合制备的自由基前体甲基丙烯酸叔丁基酯的常规自由基共振研究
5. The Protective Effects of Ferrostatin-1 (Fer-1) in Response to Excitotoxicity in Cell Mouse Hippocampal Slices [D] . Ramirez, Mireya Nael. 2018

机译：Ferrostatin-1（FER-1）对细胞小鼠海马切片兴奋毒性的保护作用
6. Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. II. The ascorbyl radical. [O] . N. J. Dodd, J. M. Giron-Conland 1975

机译：电子自旋共振研究小鼠骨髓性白血病发展过程中的变化。二。抗坏血酸基团。
7. Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. II. The ascorbyl radical. [O] . Dodd, N. J., Giron-Conland, J. M. 1975

机译：电子自旋共振研究小鼠骨髓性白血病发展过程中的变化。二。抗坏血酸基团。
8. Quantitation of Free Radicals in B6C3F1 Mouse Liver Slices on Exposure to Four Chemical Carcinogens: An EPR-Spin Trapping Study [R] . Steel-Goodwin, L. , Schmidt, W. J. , Miller, C. R. , 1996

机译：暴露于四种化学致癌物质后B6C3F1小鼠肝切片中自由基的定量：EpR-自旋诱捕研究

Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures.

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