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首页> 外文期刊>Intensive care medicine >Validation of a new method based on ultrasound velocity dilution to measure cardiac output in paediatric patients.
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Validation of a new method based on ultrasound velocity dilution to measure cardiac output in paediatric patients.

机译：验证一种基于超声速度稀释测量小儿患者心输出量的新方法。

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To validate a novel method of ultrasound dilution (COstatus(?); Transonic Systems, Ithaca, NY) for measuring cardiac output in paediatric patients after biventricular repair of congenital heart disease.Children undergoing biventricular repair of congenital heart disease were prospectively identified. Patients with significant intracardiac shunts were excluded. Postoperative cardiac output was measured by ultrasound dilution (COud) and concurrently calculated by the Fick equation (COrms) using measured oxygen consumption by respiratory mass spectrometry.Thirty-five patients were studied generating 66 individual data sets. Subjects had a median (interquartile range) age of 147 days (11, 216), weight of 4.98 kg (3.78, 6.90) and body surface area of 0.28 m(2) (0.22, 0.34). Of the patients, 66% had peripheral arterial catheters and 34% had femoral cannulation; peripheral arterial lines accounted for 6/8 of unsuccessful studies due to inability to generate sufficient flow. The site of the central venous cannula did not impact the feasibility of completing the study. A mean bias of 0.00 L/min [2 standard deviation (SD) ± 0.76 L/min] between COud and COrms was found with a percentage error of 97%. When comparing cardiac index, bias increased to 0.13 L/min/m(2) (2SD ± 2.16 L/min/m(2)).Cardiac output by ultrasound dilution showed low bias with wide limits of agreement when compared to measurement derived by the Fick equation. Although measurements through central and peripheral arterial lines were completed with minimal difficulties in the majority of patients, the application of COstatus(?) in neonates with low body surface area may be limited.
机译：为了验证一种新的超声稀释方法（COstatus（？）; Transonic Systems，Ithaca，NY），该方法可用于测量先天性心脏病的双心室修复后的小儿患者的心输出量，从而确定了先天性心脏病的双心室修复的儿童。排除有明显心脏内分流的患者。通过超声稀释度（COud）测量术后心输出量，并同时通过呼吸质谱法测量氧消耗量，通过Fick方程（COrms）进行计算。研究了35位患者，产生了66个单独的数据集。受试者的中位（四分位间距）年龄为147天（11，216），体重为4.98千克（3.78，6.90），体表面积为0.28 m（2）（0.22，0.34）。在这些患者中，有66％的患者使用了外周动脉导管，而34％的患者使用了股骨头插管。由于无法产生足够的血流，外周动脉管路占研究失败的6/8。中央静脉插管的部位不影响完成研究的可行性。发现COud和COrms之间的平均偏差为0.00 L / min [2标准偏差（SD）±0.76 L / min]，百分误差为97％。比较心脏指数时，偏倚增加至0.13 L / min / m（2）（2SD±2.16 L / min / m（2））。超声稀释产生的心输出量显示低偏倚，与通过以下方法得出的测量值相比，具有一致的限制Fick方程。尽管在大多数患者中通过中央动脉和外周动脉管路完成测量的难度很小，但COstatus（？）在体表面积低的新生儿中的应用可能受到限制。

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