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首页> 外文期刊>Internal medicine journal >Apical sparing in tako-tsubo cardiomyopathy.
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Apical sparing in tako-tsubo cardiomyopathy.

机译：tako-tsubo心肌病的根尖保留。

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摘要

BACKGROUND: Tako-tsubo cardiomyopathy (TTC) is an acute reversible cause of segmental myocardial dysfunction that is poorly understood. We have noted a variant of this condition where a tiny segment at the apex retains some contractile function. This paper delineates the frequency of this variant relative to the classical form and the clinical differences between patients suffering from the two forms. METHODS: All cases of TTC (n = 35) were identified from our infarct angiography database and separated on the basis of apical sparing (n = 14) or no apical sparing (n 21). RESULTS: Compared with the classical form, those with apical sparing were significantly younger (63 +/- 12 vs 72 +/- 13 years) and were more likely premenopausal (5/14 vs 0/21) and had higher ejection fractions (35 +/- 6% vs 32 +/- 4%). There was a trend towards higher recurrence (4/21 vs 0/14). There were no differences in time or season of presentation, precipitant stressor, premorbid drug therapy, haemodynamics at catheterization or acute outcomes. CONCLUSION: The apical sparing variant of TTC is common, accounting for 40% of cases. While the patients are younger and more likely premenopausal, there are no other distinguishing features between the classical and the variant form.
机译：背景：Tako-tsubo心肌病（TTC）是一种尚不清楚的节段性心肌功能障碍的急性可逆原因。我们注意到了这种情况的变体，其中顶点的一小段保留了一些收缩功能。本文描述了该变体相对于经典形式的频率以及两种形式患者之间的临床差异。方法：从我们的梗死血管造影数据库中识别出所有TTC病例（n = 35），并根据根尖保留（n = 14）或无根尖保留（n 21）进行分离。结果：与经典形式相比，那些有根尖保留者显着更年轻（63 +/- 12 vs 72 +/- 13岁），更可能绝经前（5/14 vs 0/21）并且射血分数更高（35 +/- 6％与32 +/- 4％）。有更高的复发趋势（4/21 vs 0/14）。表现的时间或季节，沉淀物的压力源，病态前的药物治疗，导管插入时的血流动力学或急性结局均无差异。结论：TTC的根尖保留型是常见的，占病例的40％。虽然患者较年轻，更可能是绝经前，但经典型和变型之间没有其他区别特征。

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