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Admission glucose level and in-hospital outcomes in diabetic and non-diabetic patients with ST-elevation acute myocardial infarction

机译:糖尿病和非糖尿病合并ST段抬高的急性心肌梗死患者的入院血糖水平和住院结局

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Background Hyperglycemia on admission is a predictor of an unfavorable prognosis in patients with STelevation Acute Myocardial Infarction (AMI). Data concerning associations between an elevated glucose level on admission and other in-hospital complications are still limited. Methods A total of 1,137 AMI patients with complete admission blood glucose level (ABGL) analysis were identified and stratified according to ABGL. Results A total of 16.1% patients had admission glucose level <5 mmol/L, 36.1% <7 mmol/L, 20.2% <9 mmol/L, 9.9% <11 mmol/L and 17.7% ≥11 mmol/L. Compared with the euglycemia group, both the hypoand hyperglycemia groups were associated with higher in-hospital mortality. In-hospital mortality of diabetic patients with hypoglycemia (12.2%) was higher than that of diabetic patients with either euglycemia or mild hyperglycemia (11.1%, or 10.7% relatively). The same results were seen in non-diabetic patients. In the logistic regression analysis, admission glucose and cardiac function of Killip grade were the independent predictors of in-hospital death for patients with AMI. Conclusion Elevated admission glucose levels are associated with an increased risk of life-threatening complications in diabetic and non-diabetic AMI patients. Compared with the euglycemia group, hypoglycemia was associated with a higher trend of in-hospital mortality.
机译:背景入院时高血糖是STelevation急性心肌梗死(AMI)患者预后不良的预测指标。关于入院时血糖水平升高与其他医院内并发症之间关联的数据仍然有限。方法对1137例AMI患者进行完全入院血糖(ABGL)分析,并根据ABGL进行分层。结果共有16.1%的患者入院血糖水平<5 mmol / L,36.1%<7 mmol / L,20.2%<9 mmol / L,9.9%<11 mmol / L和17.7%≥11mmol / L。与正常血糖组相比,低血糖和高血糖组均与较高的院内死亡率相关。患有低血糖的糖尿病患者的院内死亡率(12.2%)高于患有高血糖或轻度高血糖的糖尿病患者的院内死亡率(分别为11.1%或10.7%)。在非糖尿病患者中也观察到了相同的结果。在逻辑回归分析中,入院血糖和Killip级心脏功能是AMI患者住院死亡的独立预测因子。结论糖尿病和非糖尿病AMI患者的入院血糖升高与危及生命的并发症风险增加有关。与正常血糖组相比,低血糖与院内死亡率升高趋势相关。

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