Thalidomide in angiodysplasia-related bleeding

Boey J. P.; Hahn U.; Sagheer S.; McRae S. J.

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Thalidomide in angiodysplasia-related bleeding

机译：沙利度胺治疗血管增生相关性出血

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Gastrointestinal haemorrhage from angiodysplastic lesions is not only difficult to identify, but often refractory to endoscopic intervention. Patients often require substantial transfusion support. Thalidomide has emerged as a promising medical strategy in angiodysplasia-related bleeding. We present our experience and report the findings from a review of the literature. Despite its side-effect profile, thalidomide remains the therapeutic modality with the best evidence in this difficult clinical scenario.

机译：血管增生性病变引起的胃肠道出血不仅难以识别，而且内镜干预通常难以治愈。患者通常需要大量的输血支持。沙利度胺已成为血管增生相关出血的一种有前途的医学策略。我们介绍我们的经验并报告从文献回顾中得出的结论。尽管沙利度胺有副作用，但在这种困难的临床情况下，沙利度胺仍然是具有最佳证据的治疗方法。

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来源
《Internal medicine journal》 |2015年第9期|共5页
作者
Boey J. P.; Hahn U.; Sagheer S.; McRae S. J.;
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正文语种 eng
中图分类内科学;
关键词
angiodysplasia; thalidomide; gastrointestinal haemorrhage; Von Willebrand disease;

机译：血管增生;沙利度胺;胃肠道出血;冯·威勒布兰德病;

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1. Thalidomide in angiodysplasia-related bleeding [J] . Boey J. P., Hahn U., Sagheer S., Internal medicine journal . 2015,第9期

机译：沙利度胺治疗血管增生相关性出血
2. Angiogenesis inhibitors for treatment of angiodysplasia-related gastrointestinal bleeding [J] . Bauditz J DMW: Deutsche Medizinische Wochenschrift . 2009,第38期

机译：血管生成抑制剂治疗与血管增生相关的胃肠道出血
3. Thalidomide Use Reduces Risk of Refractory Gastrointestinal Bleeding in Patients with Continuous Flow Left Ventricular Assist Devices [J] . Management science: Journal of the Institute of Management Sciences . 2020,第6期

机译：沙利度胺用于连续流动左心室辅助装置的患者降低难治性胃肠道出血的风险
4. THE CO-TOLERANCE OF PT AND PT-RU CATALYST WITH AIR-BLEEDING AND THE EFECT OF IONOMER CONTENT IN CATALYST LAYER ON CO-TOLERANCE WITHOUT AIR-BLEEDING [C] . Tomoyuki Tada, Masahiko Inoue 2002 Fuel Cell Seminar Fuel Cells-Reliable, Clean Energy for the World Abstracts Nov 18-21, 2002 Palm Springs, California . 2002

机译：PT和PT-RU催化剂与空气渗漏的协同耐受性以及催化剂层中离聚物含量对无空气渗漏的协同耐受性的影响
5. Risk Management of Thalidomide in Jordan: An Application of the World Health Organization's Health Systems Framework [D] . Shroukh, Wejdan A. 2020

机译：约旦沙利度胺的风险管理：世界卫生组织卫生系统框架的应用
6. Thalidomide for refractory gastrointestinal bleeding from vascular malformations in patients with significant comorbidities [O] . Alexis Mae Bayudan, Chien-Huan Chen 2020

机译：苏达胺用于难治性胃肠道出血从患有显着的合并症的患者中血管畸形
7. Thalidomide for the Management of Bleeding Episodes in Patients with Hereditary Hemorrhagic Telangiectasia: Effects on Epistaxis Severity Score and Quality of Life [O] . Mehmet Baysal, Elif Ümit, Hakkı Onur Kırkızlar, 2019

机译：沙利度胺用于管理遗传出血性毛细管扩诊患者的出血发作：对existaxis严重程度和生活质量的影响
8. Teratogen Metabolism: Spontaneous Decay Hydrolysis Products of Thalidomide and Thalidomide Analogue Are Not Activated by Liver Microsomes [R] . Braun, A. G., Weinreb, S. L. 1983

机译：致畸代谢：沙利度胺和沙利度胺类似物的自发衰变水解产物未被肝微粒体活化

Thalidomide in angiodysplasia-related bleeding

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