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首页> 外文期刊>International journal of antimicrobial agents >Resistance to macrolides in Group A streptococci from the European section of Turkey: genetic and phenotypic characterization
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Resistance to macrolides in Group A streptococci from the European section of Turkey: genetic and phenotypic characterization

机译:土耳其欧洲部分对A组链球菌大环内酯类药物的耐药性:遗传和表型表征

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摘要

The aim of this study was to determine the susceptibilities to macrolides of Group A streptococcal isolates from the European section of Turkey. In the case of resistant isolates, the patterns and genetic mechanisms of erythromycin resistance were studied. Seven (2.7%) of the 260 isolates were resistant to erythromycin. Four of them showed the M phenotype and harboured mefA genes whereas three isolates showed the inducible macrolide, lincosamide and streptogramin B resistance phenotype and harboured ermTR genes. In the European section of Turkey, the current resistance rate of Group A streptococci to macrolides remains low. (C) 2002 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved. [References: 15]
机译:这项研究的目的是确定来自土耳其欧洲部分的A组链球菌分离物对大环内酯类药物的敏感性。对于耐药菌株,研究了红霉素耐药的模式和遗传机制。 260株分离株中有7株(2.7%)对红霉素有抗药性。其中四个显示M表型并带有mefA基因,而三个分离株显示可诱导的大环内酯,林可酰胺和链霉菌素B抗性表型并带有ermTR基因。在土耳其的欧洲部分,A组链球菌目前对大环内酯类药物的耐药率仍然很低。 (C)2002 Elsevier Science B.V.和国际化学疗法学会。版权所有。 [参考:15]

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