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Extended Paired Dependences' Test

机译:扩展成对依赖性测试

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摘要

This paper deals with a special task following experimental practice in molecular biology. A special test construction was accomplished for this purpose. A test named Extended Paired Dependences' Test can execute paired experiments in the following way. For the jth individual (a person, a patient, an animal, a microorganism etc.) experimental samples (dependences) in the number M_(j,diseased) are provided and simultaneously experimental samples in the number M_(j,healthy), where j = 1,2,..., J. Generally, the numbers M_(j,diseased) and M_(j,healthy) need not be the same. Withal, symbol M_(j,diseased) represents number of samples obtained from, e.g., tumor tissue and M_(j,healthy) represents the number of samples obtained from healthy tissue at the same jth person. Symbol J represents the number of examined individuals (persons, patients, animals, microorganisms etc.). This test construction is relatively easily enabled with the help of the definition matrix approach. In practice, a need of the test can occur very often for miscellaneous reasons. E.g., some samples are not well done for experimental (anatomical, biochemical, etc.) reasons. Sometimes, a making of further samples can be financially too expensive or, simply, unworkable (e.g., for ethical reasons).
机译:本文根据分子生物学的实验实践处理一项特殊任务。为此完成了特殊的测试构造。名为扩展配对依赖测试的测试可以通过以下方式执行配对实验。对于第j个个体(人,患者,动物,微生物等),提供了M_(j,病态)数的实验样品(依存关系),同时提供了M_(j,健康)数的实验样品(依存关系),其中j = 1,2,...,J。通常,数字M_(j,diseased)和M_(j,healthy)不必相同。总的来说,符号M_(j,患病)代表从例如肿瘤组织获得的样品数,而M_(j,健康)代表从同一人的健康组织获得的样品数。符号J代表受检人员(人员,患者,动物,微生物等)的数量。借助定义矩阵方法,可以相对容易地启用此测试构造。实际上,出于其他原因,经常需要进行测试。例如,由于实验(解剖学,生化等)原因,有些样品做得不好。有时,制作更多的样本可能在经济上过于昂贵,或者根本就不可行(例如,出于道德原因)。

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