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首页> 外文期刊>International Journal of Biological Macromolecules: Structure, Function and Interactions >Particles of liquid-crystalline dispersions formed by (nucleic acid-rare earth element) complexes as a potential platform for neutron capture therapy
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Particles of liquid-crystalline dispersions formed by (nucleic acid-rare earth element) complexes as a potential platform for neutron capture therapy

机译:由(核酸-稀土元素)配合物形成的液晶分散体颗粒,可作为中子俘获治疗的潜在平台

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摘要

Microscopic size particles of the cholesteric double-stranded DNA (RNA) liquid-crystalline dispersions, containing the ions of the rare earth elements in their content, have been obtained for the first time. The properties of these particles differ from those of classical DNA cholesterics noticeably. The local concentration of the rare earth elements in a particle reaches 200 mg/ml. The particles of the liquid-crystalline dispersion of the (DNA-gadolinium) complex maintain the properties for a long time. The combination of the microscopic size of particles, high concentration of gadolinium in particles and their stability opens a way to practical application of this new biomaterial. (c) 2005 Elsevier B.V. All rights reserved.
机译:首次获得了胆甾型双链DNA(RNA)液晶分散体的微观尺寸颗粒,其中包含稀土元素的离子。这些颗粒的性质明显不同于传统的DNA胆甾型。颗粒中稀土元素的局部浓度达到200 mg / ml。 (DNA-d)络合物的液晶分散体的颗粒长时间保持性能。颗粒的微观尺寸,颗粒中high的高浓度及其稳定性的结合为这种新型生物材料的实际应用开辟了道路。 (c)2005 Elsevier B.V.保留所有权利。

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