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首页> 外文期刊>International Journal of Biometeorology: Journal of the International Society of Biometeorology >Effect of high altitude on sensitivity to the taste of phenylthiocarbamide
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Effect of high altitude on sensitivity to the taste of phenylthiocarbamide

机译：海拔高度对苯硫脲酰胺敏感性的影响

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摘要

Sensitivity to the taste of phenylthiocarbamide (PTC) was studied using the Harris-Kalmus method in healthy human volunteers at sea level and then subsequently at an altitude of 3500 m over a period of 3 weeks, after which they were brought back to sea level. Blood sugar, insulin and blood cortisol levels were estimated weekly. The results indicated that, out of 51 subjects studied, 26 (55%) were PTC tasters at sea level. Eight of those unable to taste PTC at sea level tested as tasters at high altitude, and 2 of them reverted to being non-tasters on return to sea level. In the blood, an increase in cortisol and blood insulin levels was seen without any significant change in sugar levels. All the changes recorded at high altitude tended to return to basal values after re-induction to sea level. The study suggests that high-altitude hypoxia in some way, possibly involving changes in hormonal profile among other factors, causes an alteration in sensitivity to the taste of PTC, resulting in some of the individuals shifting to lower PTC sensitivity.
机译：使用Harris-Kalmus方法在健康的人类志愿者中研究了对苯硫脲（PTC）味道的敏感性，然后在海平面上，然后在3周内于3500 m的海拔高度将其放回海平面。每周估计血糖，胰岛素和血液皮质醇水平。结果表明，在研究的51位受试者中，有26位（55％）是海平面的PTC品尝师。无法在海平面上品尝PTC的人中有8人在高海拔地区作为品尝师进行了测试，其中2人在返回海平面后恢复为非品酒师。在血液中，观察到皮质醇和血液胰岛素水平增加，而糖水平没有任何显着变化。再次记录到海平面之后，在高海拔处记录的所有变化都趋于恢复到基础值。该研究表明，高海拔缺氧可能以某种方式引起荷尔蒙变化，其中包括其他因素，导致对PTC味觉的敏感性发生改变，从而导致某些个体转变为较低的PTC敏感性。

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