• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of biomedical nanoscience and nanotechnology >The characterisation of the behaviour and gill toxicity of CdS/CdTe quantum dots in rainbow trout (Oncorhynchus mykiss)
【24h】

The characterisation of the behaviour and gill toxicity of CdS/CdTe quantum dots in rainbow trout (Oncorhynchus mykiss)

机译：CdS / CdTe量子点在虹鳟鱼中的行为和g毒性的表征

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The increasing commercial application of nanomaterials is raising concerns about their potential release to aquatic environments. The purpose of this study was to examine the behaviour in freshwater of capped CdS/CdTe quantum dots and the sublethal effects on gills of rainbow trout. Rainbow trout (Oncorhynchus mykiss) were exposed to increasing concentrations of CdS/CdTe or dissolved cadmium (CdSO4) for 48 h at 15°C. The initial Cd and Te concentration in the aquarium water and size fractionation were determined. After the exposure period, the gills were analysed for labile Cd content, changes in lactate and pyruvate, total and redox status of metallothioneins (MT), lipid peroxidation, protein chaperones of the heat shock protein (Hsp) 72 family and ubiquitin conjugates. QDs were mostly between 6.8 and 25 nm suggesting aggregates. Significant increases in total and metal-binding MT, gill lactate and pyruvate levels and Hsp 72 proteins were observed while ubiquitin protein conjugates were significantly decreased by the QDs only with dissolved Cd, LPO and lactate/pyruvate ratio were not affected by the QDs. A discriminant function analysis of the biomarker responses revealed that colloidal and dissolved Cd differed significantly from each other, suggesting different modes of action.
机译：纳米材料的日益商业化应用引起人们对其潜在释放到水生环境中的担忧。这项研究的目的是检查加帽的CdS / CdTe量子点在淡水中的行为以及对虹鳟g的亚致死作用。在15°C下，虹鳟（Oncorhynchus mykiss）暴露于浓度不断增加的CdS / CdTe或溶解的镉（CdSO4）中48小时。确定了水族馆水中初始的Cd和Te浓度以及大小分级。暴露期后，分析g的不稳定Cd含量，乳酸和丙酮酸的变化，金属硫蛋白（MT）的总和氧化还原状态，脂质过氧化作用，热激蛋白（Hsp）72家族的蛋白伴侣和泛素结合物。 QD大多在6.8至25 nm之间，表明存在聚集体。观察到总和金属结合的MT，lact，乳酸和丙酮酸的水平以及Hsp 72蛋白的显着增加，而仅溶解了Cd的QD却使泛素蛋白结合物显着降低，而QD则不影响LPO和乳酸/丙酮酸的比率。生物标志物反应的判别功能分析表明，胶体和溶解的Cd彼此显着不同，表明其作用方式不同。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号