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Thermometry on the nanometre-scale for biomedical applications using NMR spectroscopy

机译:使用NMR光谱法对生物医学应用进行纳米级测温

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摘要

Accurate temperature control with high spatial resolution is a challenging research topic in nano- and biotechnology. Due to their extraordinary physical and chemical properties carbon nanotubes reveal a promising potential as biomedical agents for temperature sensoring on the cellular level. Filling carbon nanotubes with tailored materials realises nanoscaled containers in which the active content is encapsulated by a protecting carbon shell. In particular, the filling with NMR active substances allows the usage as markers and temperature sensors. Their potential for biomedical applications is highlighted by temperature dependent NMR studies giving a proof-of-concept for a non-invasive temperature control on the cellular level.
机译:具有高空间分辨率的精确温度控制是纳米技术和生物技术中一个具有挑战性的研究主题。由于其非凡的物理和化学特性,碳纳米管作为细胞水平温度传感的生物医学试剂具有广阔的发展前景。用量身定制的材料填充碳纳米管可实现纳米级容器,其中的活性成分被保护性碳壳包裹。特别地,用NMR活性物质填充允许用作标记和温度传感器。温度依赖性NMR研究突出了它们在生物医学应用中的潜力,为细胞水平的无创温度控制提供了概念验证。

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