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首页> 外文期刊>International journal of clinical practice >Clinical investigation on coexisting of duodenal ulcer and gastric cancer in China.
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Clinical investigation on coexisting of duodenal ulcer and gastric cancer in China.

机译：中国十二指肠溃疡与胃癌并存的临床研究。

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Summary The aim of this study was to investigate the prevalence of coexistent duodenal ulcer and gastric cancer in China, then to explore the features of clinical manifestations, endoscopy, pathology and possible pathogenesis. A retrospective analysis has been made on medical records in Remin Hospital, Wuhan University, Hubei Province, China from January 1991 to December 2002. 37 cases of coexistent duodenal ulcer and gastric cancer were found. 24.3% (9/37) had previous history of duodenal ulcer. 81.0% (30/37) of them lack alarm symptoms or signs and 87.1% (27/31) had alleviation in abdominal pain by acid inhibitor. Duodenal ulcer was single in all cases with seven in A(1) stage, three in A(2) stage, one in H(1) stage, one in H(2) stage, seven in S(1) stage and 18 in S(2) stage. 89.2% (33/37) of concurrent gastric cancer were in the corpus and antrum, with 78.1% (29/37) of them belonging to Bormann type II and 87.1% (27/37) being moderately differentiated adenocarcinoma. 83.7% of patients (31/37) had positive rapid urease test. The coexisting gastric cancer in patients with duodenal ulcer is infrequent but not rare. Gastroscopy screening and routine follow-up are necessary for patients with duodenal ulcer. Helicobacter pylori may be important pathogen for it. Helicobacter pylori eradication is recommended in patients with duodenal ulcer to reduce the risk of contaminant gastric cancer.
机译：总结这项研究的目的是调查在中国共存的十二指肠溃疡和胃癌的患病率，然后探讨其临床表现，内窥镜检查，病理学和可能的发病机理。对1991年1月至2002年12月在湖北省武汉市人民大学瑞敏医院的病历进行回顾性分析。发现37例十二指肠溃疡和胃癌并存。 24.3％（9/37）曾有十二指肠溃疡病史。其中81.0％（30/37）没有警报症状或体征，87.1％（27/31）有酸抑制剂缓解的腹痛。在所有情况下，十二指肠溃疡均为单发，其中A（1）期为七个，A（2）期为三个，H（1）期为一个，H（2）期为一个，S（1）期为七个，S（1）期为七个。 S（2）阶段。胃体和胃窦并发胃癌的比例为89.2％（33/37），其中II型Bormann肿瘤的比例为78.1％（29/37），中度分化的腺癌的比例为87.1％（27/37）。 83.7％（31/37）的患者快速尿素酶试验阳性。十二指肠溃疡患者中并存的胃癌很少见，但并不罕见。十二指肠溃疡患者必须进行胃镜检查和常规随访。幽门螺杆菌可能是其重要的病原体。建议在十二指肠溃疡患者中根除幽门螺杆菌，以减少污染性胃癌的风险。

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