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首页> 外文期刊>International journal of clinical oncology >Endometrioid adenocarcinoma arising in adenomyosis: elucidation by periodic magnetic resonance imaging evaluations.
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Endometrioid adenocarcinoma arising in adenomyosis: elucidation by periodic magnetic resonance imaging evaluations.

机译：子宫腺肌症发生于子宫腺肌症的子宫内膜样腺癌：通过定期磁共振成像评估进行阐明。

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摘要

There are several case reports of adenocarcinomas developing within adenomyosis. However, there is no report demonstrating the natural course from adenomyosis to adenocarcinoma. We report a patient (a 41-year-old Japanese woman) who was observed every 6 months after being diagnosed with adenomyosis at our University Hospital. Although she went through menopause at age 51, she occasionally complained subsequently of abnormal genital bleeding. Eleven years after the initial diagnosis, endometrial cytology revealed the presence of malignant cells. Pelvic magnetic resonance imaging (MRI) demonstrated replacement of the adenomyotic lesion by a poorly demarcated lesion, compared to the findings on prior MRI. Consequently, we performed a modified radical hysterectomy and pelvic lymph node dissection, under a presumptive diagnosis of adenocarcinoma arising in adenomyosis. Histological diagnosis revealed an endometrioid adenocarcinoma (G3) transformed from adenomyotic epithelium, which was classified, accordingto the International Federation of Gynecology and Obstetrics, as stage Ic, pT1cN0M0. In this patient, periodic MRI evaluations, in conjunction with pathological examination, identified the transformation from adenomyosis to adenocarcinoma.
机译：有几例腺癌内发展为腺癌的病例报告。但是，没有报道表明从腺肌病到腺癌的自然过程。我们报告一名患者（一名41岁的日本女性）在我们的大学医院被诊断出患有子宫腺肌病后每6个月进行一次观察。尽管她在51岁时经历了更年期，但偶尔还是会抱怨生殖器出血异常。初步诊断十一年后，子宫内膜细胞学检查发现存在恶性细胞。与以前的MRI检查结果相比，骨盆磁共振成像（MRI）证实了界限分叉的病变取代了腺肌病病变。因此，我们在对子宫腺肌病引起的腺癌的推测性诊断下，进行了改良的根治性子宫切除术和盆腔淋巴结清扫术。组织学诊断显示子宫内膜样腺癌（G3）是从子宫腺肌上皮细胞转化而来的，根据国际妇产科联合会的分类为Ic期pT1cN0M0。在该患者中，定期进行MRI评估并结合病理检查确定了从腺肌病向腺癌的转变。

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